Comparative data on cytophotometric DNA in malignant lesions of the esophagus in the chinese and japanese

Keizo Sugimachi, Yoshihiko Koga, Masaki Mori, Guo Jun Huang, Kan Yang, Ru Gang Zhang

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Cell DNA content was microspectrophotometrically determined in tissues of advanced esophageal carcinoma of 50 Chinese and 82 Japanese subjects. DNA distribution patterns were classified into Types I, II, III, and IV, according to the degree of dispersion and the peak value on the DNA histogram. The proportions of high ploidy (Types III and IV) in Chinese and Japanese patients were 68% and 81.7%, respectively. Overall 5‐year survival rates of the Chinese and Japanese were 25.3% and 19.8%, respectively. Five‐year survival rates of patients with Types II, III and IV were 45.7%, 23.8% and 0% in Chinese patients and 57.1%, 16.1%, and 0% in Japanese patients, respectively. Thus, differences in nationality were not related to the prognosis. The incidences of high ploidy group in those with an advanced esophageal carcinoma were high and were associated with a poor prognosis in both races. DNA distribution pattern of esophageal carcinoma reflected the outcome and malignant potential in the Chinese and the Japanese.

Original languageEnglish
Pages (from-to)1947-1950
Number of pages4
JournalCancer
Volume59
Issue number11
DOIs
Publication statusPublished - Jan 1 1987

Fingerprint

Esophagus
Ploidies
DNA
Carcinoma
Survival Rate
Ethnic Groups
Incidence

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Comparative data on cytophotometric DNA in malignant lesions of the esophagus in the chinese and japanese. / Sugimachi, Keizo; Koga, Yoshihiko; Mori, Masaki; Huang, Guo Jun; Yang, Kan; Zhang, Ru Gang.

In: Cancer, Vol. 59, No. 11, 01.01.1987, p. 1947-1950.

Research output: Contribution to journalArticle

Sugimachi, Keizo ; Koga, Yoshihiko ; Mori, Masaki ; Huang, Guo Jun ; Yang, Kan ; Zhang, Ru Gang. / Comparative data on cytophotometric DNA in malignant lesions of the esophagus in the chinese and japanese. In: Cancer. 1987 ; Vol. 59, No. 11. pp. 1947-1950.
@article{11c9b2ded6b64670bd9f562737c37fdb,
title = "Comparative data on cytophotometric DNA in malignant lesions of the esophagus in the chinese and japanese",
abstract = "Cell DNA content was microspectrophotometrically determined in tissues of advanced esophageal carcinoma of 50 Chinese and 82 Japanese subjects. DNA distribution patterns were classified into Types I, II, III, and IV, according to the degree of dispersion and the peak value on the DNA histogram. The proportions of high ploidy (Types III and IV) in Chinese and Japanese patients were 68{\%} and 81.7{\%}, respectively. Overall 5‐year survival rates of the Chinese and Japanese were 25.3{\%} and 19.8{\%}, respectively. Five‐year survival rates of patients with Types II, III and IV were 45.7{\%}, 23.8{\%} and 0{\%} in Chinese patients and 57.1{\%}, 16.1{\%}, and 0{\%} in Japanese patients, respectively. Thus, differences in nationality were not related to the prognosis. The incidences of high ploidy group in those with an advanced esophageal carcinoma were high and were associated with a poor prognosis in both races. DNA distribution pattern of esophageal carcinoma reflected the outcome and malignant potential in the Chinese and the Japanese.",
author = "Keizo Sugimachi and Yoshihiko Koga and Masaki Mori and Huang, {Guo Jun} and Kan Yang and Zhang, {Ru Gang}",
year = "1987",
month = "1",
day = "1",
doi = "10.1002/1097-0142(19870601)59:11<1947::AID-CNCR2820591118>3.0.CO;2-J",
language = "English",
volume = "59",
pages = "1947--1950",
journal = "Cancer",
issn = "0008-543X",
publisher = "John Wiley and Sons Inc.",
number = "11",

}

TY - JOUR

T1 - Comparative data on cytophotometric DNA in malignant lesions of the esophagus in the chinese and japanese

AU - Sugimachi, Keizo

AU - Koga, Yoshihiko

AU - Mori, Masaki

AU - Huang, Guo Jun

AU - Yang, Kan

AU - Zhang, Ru Gang

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Cell DNA content was microspectrophotometrically determined in tissues of advanced esophageal carcinoma of 50 Chinese and 82 Japanese subjects. DNA distribution patterns were classified into Types I, II, III, and IV, according to the degree of dispersion and the peak value on the DNA histogram. The proportions of high ploidy (Types III and IV) in Chinese and Japanese patients were 68% and 81.7%, respectively. Overall 5‐year survival rates of the Chinese and Japanese were 25.3% and 19.8%, respectively. Five‐year survival rates of patients with Types II, III and IV were 45.7%, 23.8% and 0% in Chinese patients and 57.1%, 16.1%, and 0% in Japanese patients, respectively. Thus, differences in nationality were not related to the prognosis. The incidences of high ploidy group in those with an advanced esophageal carcinoma were high and were associated with a poor prognosis in both races. DNA distribution pattern of esophageal carcinoma reflected the outcome and malignant potential in the Chinese and the Japanese.

AB - Cell DNA content was microspectrophotometrically determined in tissues of advanced esophageal carcinoma of 50 Chinese and 82 Japanese subjects. DNA distribution patterns were classified into Types I, II, III, and IV, according to the degree of dispersion and the peak value on the DNA histogram. The proportions of high ploidy (Types III and IV) in Chinese and Japanese patients were 68% and 81.7%, respectively. Overall 5‐year survival rates of the Chinese and Japanese were 25.3% and 19.8%, respectively. Five‐year survival rates of patients with Types II, III and IV were 45.7%, 23.8% and 0% in Chinese patients and 57.1%, 16.1%, and 0% in Japanese patients, respectively. Thus, differences in nationality were not related to the prognosis. The incidences of high ploidy group in those with an advanced esophageal carcinoma were high and were associated with a poor prognosis in both races. DNA distribution pattern of esophageal carcinoma reflected the outcome and malignant potential in the Chinese and the Japanese.

UR - http://www.scopus.com/inward/record.url?scp=0023258560&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023258560&partnerID=8YFLogxK

U2 - 10.1002/1097-0142(19870601)59:11<1947::AID-CNCR2820591118>3.0.CO;2-J

DO - 10.1002/1097-0142(19870601)59:11<1947::AID-CNCR2820591118>3.0.CO;2-J

M3 - Article

C2 - 3567857

AN - SCOPUS:0023258560

VL - 59

SP - 1947

EP - 1950

JO - Cancer

JF - Cancer

SN - 0008-543X

IS - 11

ER -