Comparison between coacervation property and secondary structure of synthetic peptides, ile-containing elastin-derived pentapeptide repeats

Iori Maeda, Suguru Taniguchi, Junko Ebina, Noriko Watanabe, Takao Hattori, Takeru Nose

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A series of Ile-containing elastin-derived peptide-analogs, (Ile-Pro-Gly-Val-Gly)n (n=7-10) possessing remarkable and reversible coacervation property were newly synthesized. In comparison with the known elastin-derived peptideanalogs, which were so-called polypeptides, the obtained 35 to 50 mer peptides, (IPGVG)n (n=7-10) were significantly low molecular sized-polypeptides. However, they clearly exhibited coacervation property as same as the polypeptides did. Because of their low molecular size, spectrographic analyses of (IPGVG)n (n=7-10) became feasible to carry out. As results of secondary structural analyses by CD and FT-IR, it was found that the coacervation property of the peptides is clearly attributed to the ordered secondary-structures, mainly, type II β-turn.

Original languageEnglish
Pages (from-to)905-910
Number of pages6
JournalProtein and Peptide Letters
Volume20
Issue number8
DOIs
Publication statusPublished - 2013

Fingerprint

Elastin
Peptides

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Structural Biology
  • Medicine(all)

Cite this

Comparison between coacervation property and secondary structure of synthetic peptides, ile-containing elastin-derived pentapeptide repeats. / Maeda, Iori; Taniguchi, Suguru; Ebina, Junko; Watanabe, Noriko; Hattori, Takao; Nose, Takeru.

In: Protein and Peptide Letters, Vol. 20, No. 8, 2013, p. 905-910.

Research output: Contribution to journalArticle

Maeda, Iori ; Taniguchi, Suguru ; Ebina, Junko ; Watanabe, Noriko ; Hattori, Takao ; Nose, Takeru. / Comparison between coacervation property and secondary structure of synthetic peptides, ile-containing elastin-derived pentapeptide repeats. In: Protein and Peptide Letters. 2013 ; Vol. 20, No. 8. pp. 905-910.
@article{9e28db31691a4f1f94513a0d1420cfdd,
title = "Comparison between coacervation property and secondary structure of synthetic peptides, ile-containing elastin-derived pentapeptide repeats",
abstract = "A series of Ile-containing elastin-derived peptide-analogs, (Ile-Pro-Gly-Val-Gly)n (n=7-10) possessing remarkable and reversible coacervation property were newly synthesized. In comparison with the known elastin-derived peptideanalogs, which were so-called polypeptides, the obtained 35 to 50 mer peptides, (IPGVG)n (n=7-10) were significantly low molecular sized-polypeptides. However, they clearly exhibited coacervation property as same as the polypeptides did. Because of their low molecular size, spectrographic analyses of (IPGVG)n (n=7-10) became feasible to carry out. As results of secondary structural analyses by CD and FT-IR, it was found that the coacervation property of the peptides is clearly attributed to the ordered secondary-structures, mainly, type II β-turn.",
author = "Iori Maeda and Suguru Taniguchi and Junko Ebina and Noriko Watanabe and Takao Hattori and Takeru Nose",
year = "2013",
doi = "10.2174/0929866511320080007",
language = "English",
volume = "20",
pages = "905--910",
journal = "Protein and Peptide Letters",
issn = "0929-8665",
publisher = "Bentham Science Publishers B.V.",
number = "8",

}

TY - JOUR

T1 - Comparison between coacervation property and secondary structure of synthetic peptides, ile-containing elastin-derived pentapeptide repeats

AU - Maeda, Iori

AU - Taniguchi, Suguru

AU - Ebina, Junko

AU - Watanabe, Noriko

AU - Hattori, Takao

AU - Nose, Takeru

PY - 2013

Y1 - 2013

N2 - A series of Ile-containing elastin-derived peptide-analogs, (Ile-Pro-Gly-Val-Gly)n (n=7-10) possessing remarkable and reversible coacervation property were newly synthesized. In comparison with the known elastin-derived peptideanalogs, which were so-called polypeptides, the obtained 35 to 50 mer peptides, (IPGVG)n (n=7-10) were significantly low molecular sized-polypeptides. However, they clearly exhibited coacervation property as same as the polypeptides did. Because of their low molecular size, spectrographic analyses of (IPGVG)n (n=7-10) became feasible to carry out. As results of secondary structural analyses by CD and FT-IR, it was found that the coacervation property of the peptides is clearly attributed to the ordered secondary-structures, mainly, type II β-turn.

AB - A series of Ile-containing elastin-derived peptide-analogs, (Ile-Pro-Gly-Val-Gly)n (n=7-10) possessing remarkable and reversible coacervation property were newly synthesized. In comparison with the known elastin-derived peptideanalogs, which were so-called polypeptides, the obtained 35 to 50 mer peptides, (IPGVG)n (n=7-10) were significantly low molecular sized-polypeptides. However, they clearly exhibited coacervation property as same as the polypeptides did. Because of their low molecular size, spectrographic analyses of (IPGVG)n (n=7-10) became feasible to carry out. As results of secondary structural analyses by CD and FT-IR, it was found that the coacervation property of the peptides is clearly attributed to the ordered secondary-structures, mainly, type II β-turn.

UR - http://www.scopus.com/inward/record.url?scp=84882436000&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84882436000&partnerID=8YFLogxK

U2 - 10.2174/0929866511320080007

DO - 10.2174/0929866511320080007

M3 - Article

C2 - 23409853

AN - SCOPUS:84882436000

VL - 20

SP - 905

EP - 910

JO - Protein and Peptide Letters

JF - Protein and Peptide Letters

SN - 0929-8665

IS - 8

ER -