Comparison of central effects of L-ornithine metabolites on the stress responses of neonatal chicks

I. Kurauchi, K. Shigemi, S. Yamada, M. Aoki, Y. Kawada, K. Morishita, D. M. Denbow, Mitsuhiro Furuse

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Recently, we observed that central administration of L-arginine attenuated the stress responses of neonatal chicks by inducing a sedative and hypnotic effect. In addition, L-ornithine, which is produced from L-arginine in the brain, appeared to interact with L-arginine during a stress response. Several putative metabolites from L-ornithine, including L-citrullme and D-ornithine, were therefore investigated in the present study. The effects of intracerebroventricular injection of L-ornithine, L-citrulline and D-ornithine were compared in chicks under an isolation-induced stress. L-ornithine greatly attenuated the stress response and induced sedative and hypnotic effects. D-ornithine weakly attenuated the stress responses, while L-citrulline had no effect.

Original languageEnglish
Pages (from-to)2580-2584
Number of pages5
JournalJournal of Animal and Veterinary Advances
Volume8
Issue number12
Publication statusPublished - Dec 1 2009

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Ornithine
ornithine
stress response
chicks
metabolites
Hypnotics and Sedatives
arginine
Arginine
citrulline
Citrulline
sedatives
injection
brain
Injections
Brain

All Science Journal Classification (ASJC) codes

  • Agronomy and Crop Science
  • veterinary(all)

Cite this

Kurauchi, I., Shigemi, K., Yamada, S., Aoki, M., Kawada, Y., Morishita, K., ... Furuse, M. (2009). Comparison of central effects of L-ornithine metabolites on the stress responses of neonatal chicks. Journal of Animal and Veterinary Advances, 8(12), 2580-2584.

Comparison of central effects of L-ornithine metabolites on the stress responses of neonatal chicks. / Kurauchi, I.; Shigemi, K.; Yamada, S.; Aoki, M.; Kawada, Y.; Morishita, K.; Denbow, D. M.; Furuse, Mitsuhiro.

In: Journal of Animal and Veterinary Advances, Vol. 8, No. 12, 01.12.2009, p. 2580-2584.

Research output: Contribution to journalArticle

Kurauchi, I, Shigemi, K, Yamada, S, Aoki, M, Kawada, Y, Morishita, K, Denbow, DM & Furuse, M 2009, 'Comparison of central effects of L-ornithine metabolites on the stress responses of neonatal chicks', Journal of Animal and Veterinary Advances, vol. 8, no. 12, pp. 2580-2584.
Kurauchi I, Shigemi K, Yamada S, Aoki M, Kawada Y, Morishita K et al. Comparison of central effects of L-ornithine metabolites on the stress responses of neonatal chicks. Journal of Animal and Veterinary Advances. 2009 Dec 1;8(12):2580-2584.
Kurauchi, I. ; Shigemi, K. ; Yamada, S. ; Aoki, M. ; Kawada, Y. ; Morishita, K. ; Denbow, D. M. ; Furuse, Mitsuhiro. / Comparison of central effects of L-ornithine metabolites on the stress responses of neonatal chicks. In: Journal of Animal and Veterinary Advances. 2009 ; Vol. 8, No. 12. pp. 2580-2584.
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