Comparison of recovery of gastric phase III motility and gastric juice output after different types of gastrointestinal reconstruction following pylorus-preserving pancreatoduodenectomy

Shunichi Takahata, Takao Ohtsuka, Toshinaga Nabae, Hiroaki Matsunaga, Kazunori Yokohata, Koji Yamaguchi, Kazuo Chijiiwa, Masao Tanaka

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21 Citations (Scopus)

Abstract

Background: Early gastric stasis is a frequent complication of pylorus-preserving pancreatoduodenectomy (PPPD). However, few reports have addressed this phenomenon in relation to the type of gastrointestinal reconstruction. We compared gastrointestinal motility and gastric juice output after two different types of gastrointestinal reconstruction following PPPD, end-to-side duodenojejunostomy after pancreaticojejunostomy and hepaticojejunostomy (group 1) and end-to-end duodenojejunostomy before pancreaticojejunostomy and hepaticojejunostomy (group 2). Method: In a total of 25 patients, 10 in group 1 and 15 in group 2, who underwent PPPD, manometry was repeated to assess gastric and jejunal motility until the first occurrence of phase III activity of gastric cyclic motor activity (CMA). The plasma level of motilin was measured in each phase of the gastric CMA and compared between the two groups. The daily volume of gastric juice output through a gastrostomy tube was also recorded for comparison. Result: There was no significant difference in the time period for recovery of gastric phase III activity and gastric juice output between the two groups. However, abnormal contractions with an increased basal pressure appeared frequently in the afferent jejunal loop only in group 1. The plasma motilin level after PPPD showed no apparent cyclic change even after the recovery of gastric phase III in either group. Conclusion: Gastrointestinal reconstructive procedures have almost no effect on the recovery of gastric CMA. The plasma motilin concentration does not play a major role in the recovery of gastric CMA in the early postoperative period after PPPD.

Original languageEnglish
Pages (from-to)596-603
Number of pages8
JournalJournal of gastroenterology
Volume37
Issue number8
DOIs
Publication statusPublished - Aug 1 2002

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Gastric Juice
Pancreaticoduodenectomy
Pylorus
Stomach
Motilin
Motor Activity
Pancreaticojejunostomy
Gastroparesis
Gastrointestinal Motility
Gastrostomy
Manometry
Postoperative Period
Pressure

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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Comparison of recovery of gastric phase III motility and gastric juice output after different types of gastrointestinal reconstruction following pylorus-preserving pancreatoduodenectomy. / Takahata, Shunichi; Ohtsuka, Takao; Nabae, Toshinaga; Matsunaga, Hiroaki; Yokohata, Kazunori; Yamaguchi, Koji; Chijiiwa, Kazuo; Tanaka, Masao.

In: Journal of gastroenterology, Vol. 37, No. 8, 01.08.2002, p. 596-603.

Research output: Contribution to journalArticle

Takahata, Shunichi ; Ohtsuka, Takao ; Nabae, Toshinaga ; Matsunaga, Hiroaki ; Yokohata, Kazunori ; Yamaguchi, Koji ; Chijiiwa, Kazuo ; Tanaka, Masao. / Comparison of recovery of gastric phase III motility and gastric juice output after different types of gastrointestinal reconstruction following pylorus-preserving pancreatoduodenectomy. In: Journal of gastroenterology. 2002 ; Vol. 37, No. 8. pp. 596-603.
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AU - Ohtsuka, Takao

AU - Nabae, Toshinaga

AU - Matsunaga, Hiroaki

AU - Yokohata, Kazunori

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AU - Chijiiwa, Kazuo

AU - Tanaka, Masao

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N2 - Background: Early gastric stasis is a frequent complication of pylorus-preserving pancreatoduodenectomy (PPPD). However, few reports have addressed this phenomenon in relation to the type of gastrointestinal reconstruction. We compared gastrointestinal motility and gastric juice output after two different types of gastrointestinal reconstruction following PPPD, end-to-side duodenojejunostomy after pancreaticojejunostomy and hepaticojejunostomy (group 1) and end-to-end duodenojejunostomy before pancreaticojejunostomy and hepaticojejunostomy (group 2). Method: In a total of 25 patients, 10 in group 1 and 15 in group 2, who underwent PPPD, manometry was repeated to assess gastric and jejunal motility until the first occurrence of phase III activity of gastric cyclic motor activity (CMA). The plasma level of motilin was measured in each phase of the gastric CMA and compared between the two groups. The daily volume of gastric juice output through a gastrostomy tube was also recorded for comparison. Result: There was no significant difference in the time period for recovery of gastric phase III activity and gastric juice output between the two groups. However, abnormal contractions with an increased basal pressure appeared frequently in the afferent jejunal loop only in group 1. The plasma motilin level after PPPD showed no apparent cyclic change even after the recovery of gastric phase III in either group. Conclusion: Gastrointestinal reconstructive procedures have almost no effect on the recovery of gastric CMA. The plasma motilin concentration does not play a major role in the recovery of gastric CMA in the early postoperative period after PPPD.

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