Comparison of treatment patterns in schizophrenia between China and Japan (2001-2009)

Yu Tao Xiang, Takahiro Kato, Taishiro Kishimoto, Gabor S. Ungvari, Helen F.K. Chiu, Tian Mei Si, Shu Yu Yang, Senta Fujii, Chee H. Ng, Naotaka Shinfuku

Research output: Contribution to journalArticle

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Abstract

Introduction: To date no study has compared the treatment patterns for schizophrenia specifically between China and Japan. This study examined the cross-national differences in the use of psychotropic drugs and electroconvulsive therapy (ECT) in schizophrenia. Method: Data on 3248 schizophrenia inpatients (n = 1524 in China and n = 1724 in Japan) were collected by either chart review or interviews during the designated 3 study periods between 2001 and 2009. Patients' socio-demographic and clinical characteristics, prescriptions of psychotropic drugs, and ECT use were recorded using a standardized protocol and data collection procedure. Results: Multivariate analyses revealed that compared to their Japanese counterparts, Chinese inpatients had a shorter length of current hospitalization, were significantly less frequently prescribed second-generation antipsychotics (except clozapine), antipsychotic polypharmacy, benzodiazepines, and mood stabilizers, and more likely to receive clozapine, antidepressants, and ECT. Discussion: Substantial variations in inpatient treatment patterns for schizophrenia were found between China and Japan. The common use of ECT and clozapine in Chinese inpatients and the frequent use of antipsychotic polypharmacy and high antipsychotic doses in Japanese inpatients need to be addressed.

Original languageEnglish
Article numbere12277
JournalAsia-Pacific Psychiatry
Volume9
Issue number4
DOIs
Publication statusPublished - Dec 1 2017

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Electroconvulsive Therapy
Inpatients
China
Schizophrenia
Japan
Antipsychotic Agents
Clozapine
Polypharmacy
Psychotropic Drugs
Therapeutics
Drug Therapy
Prescription Drugs
Benzodiazepines
Antidepressive Agents
Hospitalization
Multivariate Analysis
Demography
Interviews

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Cite this

Xiang, Y. T., Kato, T., Kishimoto, T., Ungvari, G. S., Chiu, H. F. K., Si, T. M., ... Shinfuku, N. (2017). Comparison of treatment patterns in schizophrenia between China and Japan (2001-2009). Asia-Pacific Psychiatry, 9(4), [e12277]. https://doi.org/10.1111/appy.12277

Comparison of treatment patterns in schizophrenia between China and Japan (2001-2009). / Xiang, Yu Tao; Kato, Takahiro; Kishimoto, Taishiro; Ungvari, Gabor S.; Chiu, Helen F.K.; Si, Tian Mei; Yang, Shu Yu; Fujii, Senta; Ng, Chee H.; Shinfuku, Naotaka.

In: Asia-Pacific Psychiatry, Vol. 9, No. 4, e12277, 01.12.2017.

Research output: Contribution to journalArticle

Xiang, YT, Kato, T, Kishimoto, T, Ungvari, GS, Chiu, HFK, Si, TM, Yang, SY, Fujii, S, Ng, CH & Shinfuku, N 2017, 'Comparison of treatment patterns in schizophrenia between China and Japan (2001-2009)', Asia-Pacific Psychiatry, vol. 9, no. 4, e12277. https://doi.org/10.1111/appy.12277
Xiang, Yu Tao ; Kato, Takahiro ; Kishimoto, Taishiro ; Ungvari, Gabor S. ; Chiu, Helen F.K. ; Si, Tian Mei ; Yang, Shu Yu ; Fujii, Senta ; Ng, Chee H. ; Shinfuku, Naotaka. / Comparison of treatment patterns in schizophrenia between China and Japan (2001-2009). In: Asia-Pacific Psychiatry. 2017 ; Vol. 9, No. 4.
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