Complete nucleotide sequence of the 26S rRNA gene of Physarum polycephalum: its significance in gene evolution.

T. Otsuka, H. Nomiyama, H. Yoshida, T. Kukita, S. Kuhara, Y. Sakaki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The complete nucleotide sequences of the 5.8S and 26S rRNA genes of Physarum polycephalum and the transcribed spacer between them were determined. Comparison of the sequences with those of the Escherichia coli 23S rRNA and yeast 26S rRNA genes showed that there are 16 highly homologous regions in the sequences of Physarum and E. coli and that eukaryotes have some eukaryote-specific extra sequences. The sequence immediately following the 5.8S-like region of E. coli 23S rRNA was found to be highly homologous to the 5' terminus of Physarum 26S rRNA, indicating that the eukaryote-specific 5.8S rRNA gene is derived from the 5'-terminal region of the prokaryote large rRNA gene.

Original languageEnglish
Pages (from-to)3163-3167
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume80
Issue number11
DOIs
Publication statusPublished - Jun 1983

All Science Journal Classification (ASJC) codes

  • General

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