Complete resection of unicentric Castleman disease in the superior mediastinum: A case report

Akira Haro, Erina Kuramitsu, Yasuro Fukuyama

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction Castleman disease (CD) is a rare benign lymphoproliferative disorder characterized by benign lymph node hyperplasia in a single site (unicentric CD [UCD]) or in multiple sites (multicentric CD [MCD]). Patients with UCD are usually asymptomatic; however, those with MCD usually develop fever, weight loss, and peripheral lymphadenopathy. Case presentation We describe a case of surgically resected UCD in the superior mediastinum in which the involved lymph node was surrounded by important vessels and trachea, necessitating a median sternotomy for complete resection of the tumor. Discussion Preoperative diagnosis of UCD in the thorax is very difficult, and surgical resection or excision is necessary. Complete resection is recommended for UCD because it is curative and has a 5-year survival rate of 100%. Concludion UCD should be included in the differential diagnosis of asymptomatic mediastinal tumors. Surgical resection or excision is preferred to ensure an accurate diagnosis and appropriate treatment if malignant disease cannot otherwise be ruled out.

Original languageEnglish
Pages (from-to)44-47
Number of pages4
JournalInternational Journal of Surgery Case Reports
Volume25
DOIs
Publication statusPublished - Jan 1 2016

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Giant Lymph Node Hyperplasia
Mediastinum
Lymph Nodes
Sternotomy
Lymphoproliferative Disorders
Trachea
Hyperplasia
Weight Loss
Neoplasms
Differential Diagnosis
Fever
Thorax
Survival Rate
Therapeutics
Lymphadenopathy
Multi-centric Castleman's Disease

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Complete resection of unicentric Castleman disease in the superior mediastinum : A case report. / Haro, Akira; Kuramitsu, Erina; Fukuyama, Yasuro.

In: International Journal of Surgery Case Reports, Vol. 25, 01.01.2016, p. 44-47.

Research output: Contribution to journalArticle

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