Complex segregation analysis for two-locus model: Autosomal double recessive

Norikazu Yasuda, Takehiko Sasazuki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

An autosomal doubly recessive mode of inheritance was implemented in segregation analysis, taken into account for segregation frequency, proportion of sporadic cases and ascertainment probability. Maximum likelihood scores are tabulated for some sizes of sibship. Segregation analysis thus becomes much easier with a desk calculator. The procedure has been illustrated for Graves disease.

Original languageEnglish
Pages (from-to)421-435
Number of pages15
JournalThe Japanese Journal of Human Genetics
Volume29
Issue number4
DOIs
Publication statusPublished - Dec 1 1984
Externally publishedYes

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Graves Disease

All Science Journal Classification (ASJC) codes

  • Genetics(clinical)

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Complex segregation analysis for two-locus model : Autosomal double recessive. / Yasuda, Norikazu; Sasazuki, Takehiko.

In: The Japanese Journal of Human Genetics, Vol. 29, No. 4, 01.12.1984, p. 421-435.

Research output: Contribution to journalArticle

Yasuda, Norikazu ; Sasazuki, Takehiko. / Complex segregation analysis for two-locus model : Autosomal double recessive. In: The Japanese Journal of Human Genetics. 1984 ; Vol. 29, No. 4. pp. 421-435.
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