Computational fluid dynamics comparison of impaired breathing function in French bulldogs with nostril stenosis and an examination of the efficacy of rhinoplasty

Nguyen Dang Khoa, Nguyen Lu Phuong, Kenji Tani, Kiao Inthavong, Kazuhide Ito

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Brachycephalic obstructive airway syndrome (BOAS) in dogs indicates a particular set of upper airway abnormalities found in brachycephalic dogs (e.g., French bulldogs). Stenotic nares is one of the primary BOAS-related abnormalities restricting the functional breathing of affected dogs. For severe stenosis, rhinoplasty is required to increase the accessibility of the external nostril to air; however, the specific improvement from surgery in terms of respiratory physiology and uptake of inhaled air has not been fully elucidated Method: This study employed Computational Fluid Dynamics (CFD) simulations to evaluate the effects of different stenotic intensities on airflow patterns in a total of eight French bulldog upper airways. A bulldog with severe stenosis after surgery was included to examine the efficacy of the surgical intervention. Results: The results showed homogeneous airflow distributions in healthy and mild stenosis cases and significantly accelerated airstreams at the constricted positions in moderate and severe stenosis bulldogs. The airflow resistance was over 20-fold greater in severe stenosis cases than the healthy cases. After surgery, a decrease in airflow velocity was observed in the surgical region, and the percentage of reduced airflow resistance was approximately 4%. Conclusions: This study suggests impaired breathing function in brachycephalic dogs with moderate and severe stenosis. The results also serve as a reference for veterinarians in surgical planning and monitoring bulldogs' recuperation after surgery.

Original languageEnglish
Article number104398
JournalComputers in Biology and Medicine
Volume134
DOIs
Publication statusPublished - Jul 2021

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Health Informatics

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