Computed tomography and histologic appearance of pancreatic metastases from distant sources

T. Muranaka, K. Teshima, Hiroshi Honda, T. Nanjo, K. Hanada, Y. Oshiumi

Research output: Contribution to journalArticle

Abstract

The computed tomographic and histologic appearances in 34 cases of autopsy-confirmed metastatic tumors of the pancreas including secondary malignant lymphoma are discussed. In 18 (53.8%) the pancreas appeared abnormal on computed tomography, the lesions being classified into three types: In 8 cases there was diffuse enlargement of the pancreas; in 9 cases a localized mass; and one patient had multiple low attenuated nodules within the organ. Histologic investigation revealed that metastatic carcinoma involved the pancreatic lobules. The degree of infiltration in the interlobular connective tissue was related to the invasiveness of the tumors. In the majority of cases with diffuse infiltration the pancreatic lobules were destroyed and varying degrees of proliferation of malignant cells into the interlobular septa were documented. In patients with localized infiltration there was extensive invasion of the carcinoma within the pancreatic lobule. Dilatation of the pancreatic duct and/or organ-related symptoms were occasionally seen in these cases.

Original languageEnglish
Pages (from-to)615-619
Number of pages5
JournalActa Radiologica
Volume30
Issue number6
DOIs
Publication statusPublished - Jan 1 1989
Externally publishedYes

Fingerprint

Pancreas
Tomography
Neoplasm Metastasis
Pancreatic Ducts
Connective Tissue
Dilatation
Autopsy
Lymphoma
Neoplasms
Cell Proliferation
Pancreatic Carcinoma

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Muranaka, T., Teshima, K., Honda, H., Nanjo, T., Hanada, K., & Oshiumi, Y. (1989). Computed tomography and histologic appearance of pancreatic metastases from distant sources. Acta Radiologica, 30(6), 615-619. https://doi.org/10.1177/028418518903000609

Computed tomography and histologic appearance of pancreatic metastases from distant sources. / Muranaka, T.; Teshima, K.; Honda, Hiroshi; Nanjo, T.; Hanada, K.; Oshiumi, Y.

In: Acta Radiologica, Vol. 30, No. 6, 01.01.1989, p. 615-619.

Research output: Contribution to journalArticle

Muranaka, T, Teshima, K, Honda, H, Nanjo, T, Hanada, K & Oshiumi, Y 1989, 'Computed tomography and histologic appearance of pancreatic metastases from distant sources', Acta Radiologica, vol. 30, no. 6, pp. 615-619. https://doi.org/10.1177/028418518903000609
Muranaka, T. ; Teshima, K. ; Honda, Hiroshi ; Nanjo, T. ; Hanada, K. ; Oshiumi, Y. / Computed tomography and histologic appearance of pancreatic metastases from distant sources. In: Acta Radiologica. 1989 ; Vol. 30, No. 6. pp. 615-619.
@article{d017021102fa496f898edc5a74d56c24,
title = "Computed tomography and histologic appearance of pancreatic metastases from distant sources",
abstract = "The computed tomographic and histologic appearances in 34 cases of autopsy-confirmed metastatic tumors of the pancreas including secondary malignant lymphoma are discussed. In 18 (53.8{\%}) the pancreas appeared abnormal on computed tomography, the lesions being classified into three types: In 8 cases there was diffuse enlargement of the pancreas; in 9 cases a localized mass; and one patient had multiple low attenuated nodules within the organ. Histologic investigation revealed that metastatic carcinoma involved the pancreatic lobules. The degree of infiltration in the interlobular connective tissue was related to the invasiveness of the tumors. In the majority of cases with diffuse infiltration the pancreatic lobules were destroyed and varying degrees of proliferation of malignant cells into the interlobular septa were documented. In patients with localized infiltration there was extensive invasion of the carcinoma within the pancreatic lobule. Dilatation of the pancreatic duct and/or organ-related symptoms were occasionally seen in these cases.",
author = "T. Muranaka and K. Teshima and Hiroshi Honda and T. Nanjo and K. Hanada and Y. Oshiumi",
year = "1989",
month = "1",
day = "1",
doi = "10.1177/028418518903000609",
language = "English",
volume = "30",
pages = "615--619",
journal = "Acta Radiologica",
issn = "0284-1851",
publisher = "SAGE Publications Ltd",
number = "6",

}

TY - JOUR

T1 - Computed tomography and histologic appearance of pancreatic metastases from distant sources

AU - Muranaka, T.

AU - Teshima, K.

AU - Honda, Hiroshi

AU - Nanjo, T.

AU - Hanada, K.

AU - Oshiumi, Y.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - The computed tomographic and histologic appearances in 34 cases of autopsy-confirmed metastatic tumors of the pancreas including secondary malignant lymphoma are discussed. In 18 (53.8%) the pancreas appeared abnormal on computed tomography, the lesions being classified into three types: In 8 cases there was diffuse enlargement of the pancreas; in 9 cases a localized mass; and one patient had multiple low attenuated nodules within the organ. Histologic investigation revealed that metastatic carcinoma involved the pancreatic lobules. The degree of infiltration in the interlobular connective tissue was related to the invasiveness of the tumors. In the majority of cases with diffuse infiltration the pancreatic lobules were destroyed and varying degrees of proliferation of malignant cells into the interlobular septa were documented. In patients with localized infiltration there was extensive invasion of the carcinoma within the pancreatic lobule. Dilatation of the pancreatic duct and/or organ-related symptoms were occasionally seen in these cases.

AB - The computed tomographic and histologic appearances in 34 cases of autopsy-confirmed metastatic tumors of the pancreas including secondary malignant lymphoma are discussed. In 18 (53.8%) the pancreas appeared abnormal on computed tomography, the lesions being classified into three types: In 8 cases there was diffuse enlargement of the pancreas; in 9 cases a localized mass; and one patient had multiple low attenuated nodules within the organ. Histologic investigation revealed that metastatic carcinoma involved the pancreatic lobules. The degree of infiltration in the interlobular connective tissue was related to the invasiveness of the tumors. In the majority of cases with diffuse infiltration the pancreatic lobules were destroyed and varying degrees of proliferation of malignant cells into the interlobular septa were documented. In patients with localized infiltration there was extensive invasion of the carcinoma within the pancreatic lobule. Dilatation of the pancreatic duct and/or organ-related symptoms were occasionally seen in these cases.

UR - http://www.scopus.com/inward/record.url?scp=84970301465&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84970301465&partnerID=8YFLogxK

U2 - 10.1177/028418518903000609

DO - 10.1177/028418518903000609

M3 - Article

VL - 30

SP - 615

EP - 619

JO - Acta Radiologica

JF - Acta Radiologica

SN - 0284-1851

IS - 6

ER -