Confirmation of in vitro synthesis of 2-deoxy-sc7llo-inosose, the earliest intermediate in the biosynthesis of 2-deoxystreptamine, using cell free preparations of streptomyces fradiae

Noriaki Yamauchi, Katsumi Kakinuma

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The in vitro activity of formation of 2-deoxy-scyllo-inosose, the earliest intermediate of the 2-deoxystreptamine biosynthesis, was confirmed in the precipitate fraction obtained by 30~45% saturation of ammonium sulfate from the 15,000 × g supernatant of the sonicated Streptomyces fradiae IFO 13147 cells.

Original languageEnglish
Pages (from-to)774-780
Number of pages7
JournalThe Journal of Antibiotics
Volume45
Issue number5
DOIs
Publication statusPublished - Jan 1 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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