Constipation and Colorectal Cancer Risk: The Fukuoka colorectal cancer study

Naotaka Tashiro, Sanjeev Budhathoki, Keizo Ohnaka, Kengo Toyomura, Suminori Kono, Takashi Ueki, Masao Tanaka, Yoshihiro Kakeji, Yoshihiko Maehara, Takeshi Okamura, Koji Ikejiri, Kitaroh Futami, Takafumi Maekawa, Yohichi Yasunami, Kenji Takenaka, Hitoshi Ichimiya, Reiji Terasaka

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Constipation has been suspected to be linked to colorectal cancer risk, but epidemiological evidence is inconclusive. We described the prevalence of constipation and related lifestyle factors in a community and examined the relation of constipation and other bowel habits to colorectal cancer risk. The prevalence study was based on 833 community controls in the Fukuoka Colorectal Cancer Study, and 212 cases of Dukes' stage A were used in a study on bowel habits and colorectal cancer risk. Bowel habits were assessed by in-person interview. Odds ratio (OR) and 95% confidence interval (CI) of colorectal cancer were estimated with adjustment for dietary and nondietary factors. Constipation was reported by 10.3% of men and 27.7% of women. Individuals with less frequent bowel movements had a lower intake of total energy and were physically less active. The multivariate-adjusted OR (95% CI) of colorectal cancer were 1.51 (1.02-2.25) for self-reported constipation, 1.60 (1.05-2.44) for functional constipation, and 1.24 (0.81-1.90) for infrequent bowel movements (<1 stool/day). Self-reported constipation was fairly common in Japanese adults. Constipation was associated with a moderately increased risk of colorectal cancer.

Original languageEnglish
Pages (from-to)2025-2030
Number of pages6
JournalAsian Pacific Journal of Cancer Prevention
Volume12
Issue number8
Publication statusPublished - 2011

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Constipation
Colorectal Neoplasms
Habits
Odds Ratio
Community-Institutional Relations
Confidence Intervals
Energy Intake
Life Style
Cross-Sectional Studies
Interviews

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Cancer Research

Cite this

Tashiro, N., Budhathoki, S., Ohnaka, K., Toyomura, K., Kono, S., Ueki, T., ... Terasaka, R. (2011). Constipation and Colorectal Cancer Risk: The Fukuoka colorectal cancer study. Asian Pacific Journal of Cancer Prevention, 12(8), 2025-2030.

Constipation and Colorectal Cancer Risk : The Fukuoka colorectal cancer study. / Tashiro, Naotaka; Budhathoki, Sanjeev; Ohnaka, Keizo; Toyomura, Kengo; Kono, Suminori; Ueki, Takashi; Tanaka, Masao; Kakeji, Yoshihiro; Maehara, Yoshihiko; Okamura, Takeshi; Ikejiri, Koji; Futami, Kitaroh; Maekawa, Takafumi; Yasunami, Yohichi; Takenaka, Kenji; Ichimiya, Hitoshi; Terasaka, Reiji.

In: Asian Pacific Journal of Cancer Prevention, Vol. 12, No. 8, 2011, p. 2025-2030.

Research output: Contribution to journalArticle

Tashiro, N, Budhathoki, S, Ohnaka, K, Toyomura, K, Kono, S, Ueki, T, Tanaka, M, Kakeji, Y, Maehara, Y, Okamura, T, Ikejiri, K, Futami, K, Maekawa, T, Yasunami, Y, Takenaka, K, Ichimiya, H & Terasaka, R 2011, 'Constipation and Colorectal Cancer Risk: The Fukuoka colorectal cancer study', Asian Pacific Journal of Cancer Prevention, vol. 12, no. 8, pp. 2025-2030.
Tashiro, Naotaka ; Budhathoki, Sanjeev ; Ohnaka, Keizo ; Toyomura, Kengo ; Kono, Suminori ; Ueki, Takashi ; Tanaka, Masao ; Kakeji, Yoshihiro ; Maehara, Yoshihiko ; Okamura, Takeshi ; Ikejiri, Koji ; Futami, Kitaroh ; Maekawa, Takafumi ; Yasunami, Yohichi ; Takenaka, Kenji ; Ichimiya, Hitoshi ; Terasaka, Reiji. / Constipation and Colorectal Cancer Risk : The Fukuoka colorectal cancer study. In: Asian Pacific Journal of Cancer Prevention. 2011 ; Vol. 12, No. 8. pp. 2025-2030.
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