TY - JOUR
T1 - Constituents of holothuroidea, II. Six newly identified biologically active triterpenoid glycoside sulfates from the sea cucumber Cucumaria echinata
AU - Miyamoto, Tomofumi
AU - Togawa, Kenichi
AU - Higuchi, Ryuichi
AU - Komori, Tetsuya
AU - Sasaki, Takuma
PY - 1990/1/1
Y1 - 1990/1/1
N2 - From the whole body of sea cucumber Cucumaria echinata (Cucumariidae), we recently identified six genuine holostane‐type triterpenoid glycoside sulfates designated as cucumechinoside A (1), B (2), C (3), D (4), E (5), and F (6). The structures 1–6 were determined on the basis of chemical and spectral investigations. Antitumor activities of these cucumechinosides and their solvolized compounds (10, 11, and 12) against murine lymphoma L 1210 and human epidermoid carcinoma KB cell in vitro were examined, and their antifungal and antiprotozoal activities were also investigated.
AB - From the whole body of sea cucumber Cucumaria echinata (Cucumariidae), we recently identified six genuine holostane‐type triterpenoid glycoside sulfates designated as cucumechinoside A (1), B (2), C (3), D (4), E (5), and F (6). The structures 1–6 were determined on the basis of chemical and spectral investigations. Antitumor activities of these cucumechinosides and their solvolized compounds (10, 11, and 12) against murine lymphoma L 1210 and human epidermoid carcinoma KB cell in vitro were examined, and their antifungal and antiprotozoal activities were also investigated.
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U2 - 10.1002/jlac.199019900186
DO - 10.1002/jlac.199019900186
M3 - Article
AN - SCOPUS:84986703605
SN - 0075-4617
VL - 1990
SP - 453
EP - 460
JO - Justus Liebigs Annalen der Chemie
JF - Justus Liebigs Annalen der Chemie
IS - 5
ER -