Construction of 3D tissue-like structure using functional magnetite nanoparticles

Akira Ito, Hiroyuki Honda, Masamichi Kamihira

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Magnetic nanoparticles for medical applications have been developed by many researchers. Since these nanoparticles have unique magnetic features not present in other materials, they can be applied to special medical techniques. Magnetite cationic liposomes (MCLs), one group of the cationic magnetic particles, can be used as carriers to introduce magnetite nanoparticles into target cells since their positively charged surface interacts with the negatively charged cell surface. Magnetite nanoparticles conjugated with antibodies (antibody-conjugated magnetoliposomes, AMLs) are applicable to introduce magnetite nanoparticles specifically into target cells, even when target cells coexist with other kinds of cells. Since the cells labeled with magnetite nanoparticles could be manipulated using magnets, we applied this technique to tissue engineering and termed it 'magnetic force-based tissue engineering (Mag-TE)'. Both magnetic force and functionalized magnetite nanoparticles were used in a process of tissue engineering: construction of multilayered cell sheet-like structures and tubular structures. Thus, the applications of these functionalized magnetite nanoparticles with their unique features will further improve tissue engineering techniques.

Original languageEnglish
Pages (from-to)21-28
Number of pages8
JournalYakugaku Zasshi
Volume128
Issue number1
DOIs
Publication statusPublished - Jan 1 2008

Fingerprint

Magnetite Nanoparticles
Tissue Engineering
Nanoparticles
Ferrosoferric Oxide
Magnets
Antibodies
Liposomes
Research Personnel

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

Cite this

Construction of 3D tissue-like structure using functional magnetite nanoparticles. / Ito, Akira; Honda, Hiroyuki; Kamihira, Masamichi.

In: Yakugaku Zasshi, Vol. 128, No. 1, 01.01.2008, p. 21-28.

Research output: Contribution to journalReview article

@article{20118ba13bdb45a8966017f5c807160e,
title = "Construction of 3D tissue-like structure using functional magnetite nanoparticles",
abstract = "Magnetic nanoparticles for medical applications have been developed by many researchers. Since these nanoparticles have unique magnetic features not present in other materials, they can be applied to special medical techniques. Magnetite cationic liposomes (MCLs), one group of the cationic magnetic particles, can be used as carriers to introduce magnetite nanoparticles into target cells since their positively charged surface interacts with the negatively charged cell surface. Magnetite nanoparticles conjugated with antibodies (antibody-conjugated magnetoliposomes, AMLs) are applicable to introduce magnetite nanoparticles specifically into target cells, even when target cells coexist with other kinds of cells. Since the cells labeled with magnetite nanoparticles could be manipulated using magnets, we applied this technique to tissue engineering and termed it 'magnetic force-based tissue engineering (Mag-TE)'. Both magnetic force and functionalized magnetite nanoparticles were used in a process of tissue engineering: construction of multilayered cell sheet-like structures and tubular structures. Thus, the applications of these functionalized magnetite nanoparticles with their unique features will further improve tissue engineering techniques.",
author = "Akira Ito and Hiroyuki Honda and Masamichi Kamihira",
year = "2008",
month = "1",
day = "1",
doi = "10.1248/yakushi.128.21",
language = "English",
volume = "128",
pages = "21--28",
journal = "Yakugaku Zasshi",
issn = "0031-6903",
publisher = "公益社団法人 日本薬学会",
number = "1",

}

TY - JOUR

T1 - Construction of 3D tissue-like structure using functional magnetite nanoparticles

AU - Ito, Akira

AU - Honda, Hiroyuki

AU - Kamihira, Masamichi

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Magnetic nanoparticles for medical applications have been developed by many researchers. Since these nanoparticles have unique magnetic features not present in other materials, they can be applied to special medical techniques. Magnetite cationic liposomes (MCLs), one group of the cationic magnetic particles, can be used as carriers to introduce magnetite nanoparticles into target cells since their positively charged surface interacts with the negatively charged cell surface. Magnetite nanoparticles conjugated with antibodies (antibody-conjugated magnetoliposomes, AMLs) are applicable to introduce magnetite nanoparticles specifically into target cells, even when target cells coexist with other kinds of cells. Since the cells labeled with magnetite nanoparticles could be manipulated using magnets, we applied this technique to tissue engineering and termed it 'magnetic force-based tissue engineering (Mag-TE)'. Both magnetic force and functionalized magnetite nanoparticles were used in a process of tissue engineering: construction of multilayered cell sheet-like structures and tubular structures. Thus, the applications of these functionalized magnetite nanoparticles with their unique features will further improve tissue engineering techniques.

AB - Magnetic nanoparticles for medical applications have been developed by many researchers. Since these nanoparticles have unique magnetic features not present in other materials, they can be applied to special medical techniques. Magnetite cationic liposomes (MCLs), one group of the cationic magnetic particles, can be used as carriers to introduce magnetite nanoparticles into target cells since their positively charged surface interacts with the negatively charged cell surface. Magnetite nanoparticles conjugated with antibodies (antibody-conjugated magnetoliposomes, AMLs) are applicable to introduce magnetite nanoparticles specifically into target cells, even when target cells coexist with other kinds of cells. Since the cells labeled with magnetite nanoparticles could be manipulated using magnets, we applied this technique to tissue engineering and termed it 'magnetic force-based tissue engineering (Mag-TE)'. Both magnetic force and functionalized magnetite nanoparticles were used in a process of tissue engineering: construction of multilayered cell sheet-like structures and tubular structures. Thus, the applications of these functionalized magnetite nanoparticles with their unique features will further improve tissue engineering techniques.

UR - http://www.scopus.com/inward/record.url?scp=38149052950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38149052950&partnerID=8YFLogxK

U2 - 10.1248/yakushi.128.21

DO - 10.1248/yakushi.128.21

M3 - Review article

VL - 128

SP - 21

EP - 28

JO - Yakugaku Zasshi

JF - Yakugaku Zasshi

SN - 0031-6903

IS - 1

ER -