Construction of a transplantable tissue-engineered artificial peritoneum

H. Kuga, T. Morisaki, K. Nakamura, Hideya Ohnishi, T. Matsuda, K. Sueishi, M. Tanaka, M. Katano

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: Peritoneal defects lead to serious postoperative problems. Thus the development of physiological material to cover peritoneal defects is very desirable. Aim: The aim of this study was to develop a transplantable artificial peritoneum. Method: The artificial peritoneum consisted of collagen gel, fibroblasts, and mesothelial cells, and histological features were analyzed. The artificial peritoneum at the site of a peritoneal defect in the rat was transplanted to the abdominal wall. Results: Histological examination revealed that the artificial peritoneum consisted of a flat mesothelial monolayer upon a stromal matrix. All transplanted artificial peritoneums adapted well to the host and prevented severe adhesion. Conclusion: Our artificial peritoneum may be a useful transplantable bioengineered material for repair of surgical peritoneal defects.

Original languageEnglish
Pages (from-to)323-330
Number of pages8
JournalEuropean Surgical Research
Volume36
Issue number5
DOIs
Publication statusPublished - Oct 6 2004

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Peritoneum
Abdominal Wall
Collagen
Fibroblasts
Gels

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Kuga, H., Morisaki, T., Nakamura, K., Ohnishi, H., Matsuda, T., Sueishi, K., ... Katano, M. (2004). Construction of a transplantable tissue-engineered artificial peritoneum. European Surgical Research, 36(5), 323-330. https://doi.org/10.1159/000079919

Construction of a transplantable tissue-engineered artificial peritoneum. / Kuga, H.; Morisaki, T.; Nakamura, K.; Ohnishi, Hideya; Matsuda, T.; Sueishi, K.; Tanaka, M.; Katano, M.

In: European Surgical Research, Vol. 36, No. 5, 06.10.2004, p. 323-330.

Research output: Contribution to journalArticle

Kuga, H, Morisaki, T, Nakamura, K, Ohnishi, H, Matsuda, T, Sueishi, K, Tanaka, M & Katano, M 2004, 'Construction of a transplantable tissue-engineered artificial peritoneum', European Surgical Research, vol. 36, no. 5, pp. 323-330. https://doi.org/10.1159/000079919
Kuga, H. ; Morisaki, T. ; Nakamura, K. ; Ohnishi, Hideya ; Matsuda, T. ; Sueishi, K. ; Tanaka, M. ; Katano, M. / Construction of a transplantable tissue-engineered artificial peritoneum. In: European Surgical Research. 2004 ; Vol. 36, No. 5. pp. 323-330.
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