Continuous ictal discharges with high frequency oscillations confined to the non-sclerotic hippocampus in an epileptic patient with radiation-induced cavernoma in the lateral temporal lobe

Nobutaka Mukae, Takato Morioka, Michiko Torio, Ayumi Sakata, Satoshi Suzuki, Koji Iihara

Research output: Contribution to journalArticle

Abstract

Background: Intraoperative electrocorticography (iECoG) recording is recommended for treating cavernoma related epilepsy. However, “interictal” paroxysmal activities are generally recordable but are not always identical to the epileptogenic zone. Case description: We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. iECoG revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical “ictal” discharges with high-frequency oscillations (HFO), confined to the histologically non-sclerotic hippocampus, were recorded. Following additional hippocampectomy, a good seizure outcome was obtained. Conclusion: iECoG and HFO analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.

Original languageEnglish
Pages (from-to)87-91
Number of pages5
JournalEpilepsy and Behavior Case Reports
Volume11
DOIs
Publication statusPublished - Jan 1 2019

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Temporal Lobe
Hippocampus
Stroke
Radiation
Epilepsy
Seizures
Electrocorticography

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

Cite this

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title = "Continuous ictal discharges with high frequency oscillations confined to the non-sclerotic hippocampus in an epileptic patient with radiation-induced cavernoma in the lateral temporal lobe",
abstract = "Background: Intraoperative electrocorticography (iECoG) recording is recommended for treating cavernoma related epilepsy. However, “interictal” paroxysmal activities are generally recordable but are not always identical to the epileptogenic zone. Case description: We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. iECoG revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical “ictal” discharges with high-frequency oscillations (HFO), confined to the histologically non-sclerotic hippocampus, were recorded. Following additional hippocampectomy, a good seizure outcome was obtained. Conclusion: iECoG and HFO analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.",
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T1 - Continuous ictal discharges with high frequency oscillations confined to the non-sclerotic hippocampus in an epileptic patient with radiation-induced cavernoma in the lateral temporal lobe

AU - Mukae, Nobutaka

AU - Morioka, Takato

AU - Torio, Michiko

AU - Sakata, Ayumi

AU - Suzuki, Satoshi

AU - Iihara, Koji

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: Intraoperative electrocorticography (iECoG) recording is recommended for treating cavernoma related epilepsy. However, “interictal” paroxysmal activities are generally recordable but are not always identical to the epileptogenic zone. Case description: We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. iECoG revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical “ictal” discharges with high-frequency oscillations (HFO), confined to the histologically non-sclerotic hippocampus, were recorded. Following additional hippocampectomy, a good seizure outcome was obtained. Conclusion: iECoG and HFO analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.

AB - Background: Intraoperative electrocorticography (iECoG) recording is recommended for treating cavernoma related epilepsy. However, “interictal” paroxysmal activities are generally recordable but are not always identical to the epileptogenic zone. Case description: We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. iECoG revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical “ictal” discharges with high-frequency oscillations (HFO), confined to the histologically non-sclerotic hippocampus, were recorded. Following additional hippocampectomy, a good seizure outcome was obtained. Conclusion: iECoG and HFO analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.

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