TY - JOUR
T1 - Contribution of L-type Ca2+ channels to long-term enhancement of high K+-evoked release of dopamine from rat striatal slices
AU - Koizumi, Schuichi
AU - Kataoka, Yasufumi
AU - Inoue, Kazuhide
AU - Kohzuma, Masami
AU - Niwa, Masami
AU - Taniyama, Kohtaro
PY - 1995/3/3
Y1 - 1995/3/3
N2 - Pre-treatment with BAY K 8644, an L-type voltage-gated Ca2+ channels agonist, produced long-term enhancement (LTE) of over 2 h of high K+-evoked dopamine release from rat striatal slices. Exposure to BAY K 8644 under Ca2+-free conditions did not enhance this release. Thus, a transient activation of L-type voltage-gated Ca2+ channels followed by Ca2+ entry can trigger LTE of the evoked DA release from striatal tissues. This type of LTE in the striatum underlines the importance of presynaptic mechanisms, including L-type voltage-gated Ca2+ channels of 'long-term potentiation' expression.
AB - Pre-treatment with BAY K 8644, an L-type voltage-gated Ca2+ channels agonist, produced long-term enhancement (LTE) of over 2 h of high K+-evoked dopamine release from rat striatal slices. Exposure to BAY K 8644 under Ca2+-free conditions did not enhance this release. Thus, a transient activation of L-type voltage-gated Ca2+ channels followed by Ca2+ entry can trigger LTE of the evoked DA release from striatal tissues. This type of LTE in the striatum underlines the importance of presynaptic mechanisms, including L-type voltage-gated Ca2+ channels of 'long-term potentiation' expression.
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U2 - 10.1016/0304-3940(95)11341-X
DO - 10.1016/0304-3940(95)11341-X
M3 - Article
C2 - 7540271
AN - SCOPUS:0028987229
SN - 0304-3940
VL - 187
SP - 123
EP - 126
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 2
ER -