Control of the protein adsorption on honeycomb film by changing the pore size of honeycomb films

Hiroshi Sunami, Masaru Tanaka, Sadaaki Yamamoto, Emiko Ito, Masatsugu Shimomura

Research output: Contribution to conferencePaper

Abstract

Micro fabrication of cell culture substrates is one of the most significant subjects in the field of biomaterial research. Recently we found that the proliferation of endothelial cells were influenced by the pore size of microporous polymer film (honeycomb film). It has been reported that adsorbed proteins on substrate play vital role in mediating cell proliferation. In order to elucidate the effect of the pore size of honeycomb films as a scaffold for cell culture, the observation of protein adsorption on honeycomb films during cell culture is needed. It was found the adsorbed protein structure on honeycomb films were greatly changed by changing pore size of honeycomb film. Further development of this approach should lead to surfaces which can control cell proliferation by changing the pore size of honeycomb films.

Original languageEnglish
Number of pages1
Publication statusPublished - Oct 19 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006

Other

Other55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period5/24/065/26/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Sunami, H., Tanaka, M., Yamamoto, S., Ito, E., & Shimomura, M. (2006). Control of the protein adsorption on honeycomb film by changing the pore size of honeycomb films. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.