Control status of atherosclerotic cardiovascular risk factors among Japanese high-risk subjects

Analyses of a Japanese health check database from 2008 to 2011

Koji Hasegawa, Kazuhisa Tsukamoto, Motoei Kunimi, Koichi Asahi, Kunitoshi Iseki, Toshiki Moriyama, Kunihiro Yamagata, Kazuhiko Tsuruya, Shouichi Fujimoto, Ichiei Narita, Tsuneo Konta, Masahide Kondo, Kenjiro Kimura, Yasuo Ohashi, Tsuyoshi Watanabe

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Aims: Several guidelines propose target levels (TLs) of atherosclerotic risk factors (ARFs) to reduce atherosclerotic cardiovascular diseases; however, few data are available regarding the attainment statuses of TLs in Japan. In this study, utilizing the data obtained from the annual “Specific Health Check and Guidance in Japan” conducted from 2008 to 2011 (approximately 280,000 subjects each year), we determined TL attainments of ARFs in cardiovascular high-risk subjects. Methods: Those who had suffered from cerebrovascular disease (pCVD) or coronary heart disease (pCHD) or were receiving diabetes mellitus treatment (DM) were selected, and the rates of subjects that attained TLs of blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TGs) and glycated hemoglobin (HbA1c) were analyzed. Results: Approximately 70% of pCVD or pCHD and 35% of subjects with DM attained TLs of BP. With regard to HbA1c, >90% of pCVD or pCHD and approximately 50% of subjects with DM attained TLs. With regard to LDL-C, <25% of pCHD females and approximately 35% of pCHD males and 50%-55% of subjects with pCVD or DM attained TLs. The TL-attainment rates of HDL-C and TGs were approximately 90% and 75%, respectively, for the three diseases. Analyses of time course changes in their attainment statuses revealed that the attainment rates of BP and LDL-C significantly improved in all the diseases. Conclusions: TL-attainment rates of BP and LDL-C were not as high as those for HDL-C, TGs, and HbA1c; however, they both showed highly significant improvements during the study period.

Original languageEnglish
Pages (from-to)991-1003
Number of pages13
JournalJournal of atherosclerosis and thrombosis
Volume23
Issue number8
DOIs
Publication statusPublished - Jan 1 2016

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Coronary Disease
LDL Cholesterol
Health
Databases
Diabetes Mellitus
HDL Cholesterol
Blood Pressure
Blood pressure
Medical problems
Japan
Triglycerides
Cerebrovascular Disorders
Glycosylated Hemoglobin A
Cardiovascular Diseases
Guidelines

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Biochemistry, medical

Cite this

Control status of atherosclerotic cardiovascular risk factors among Japanese high-risk subjects : Analyses of a Japanese health check database from 2008 to 2011. / Hasegawa, Koji; Tsukamoto, Kazuhisa; Kunimi, Motoei; Asahi, Koichi; Iseki, Kunitoshi; Moriyama, Toshiki; Yamagata, Kunihiro; Tsuruya, Kazuhiko; Fujimoto, Shouichi; Narita, Ichiei; Konta, Tsuneo; Kondo, Masahide; Kimura, Kenjiro; Ohashi, Yasuo; Watanabe, Tsuyoshi.

In: Journal of atherosclerosis and thrombosis, Vol. 23, No. 8, 01.01.2016, p. 991-1003.

Research output: Contribution to journalArticle

Hasegawa, K, Tsukamoto, K, Kunimi, M, Asahi, K, Iseki, K, Moriyama, T, Yamagata, K, Tsuruya, K, Fujimoto, S, Narita, I, Konta, T, Kondo, M, Kimura, K, Ohashi, Y & Watanabe, T 2016, 'Control status of atherosclerotic cardiovascular risk factors among Japanese high-risk subjects: Analyses of a Japanese health check database from 2008 to 2011', Journal of atherosclerosis and thrombosis, vol. 23, no. 8, pp. 991-1003. https://doi.org/10.5551/jat.31906
Hasegawa, Koji ; Tsukamoto, Kazuhisa ; Kunimi, Motoei ; Asahi, Koichi ; Iseki, Kunitoshi ; Moriyama, Toshiki ; Yamagata, Kunihiro ; Tsuruya, Kazuhiko ; Fujimoto, Shouichi ; Narita, Ichiei ; Konta, Tsuneo ; Kondo, Masahide ; Kimura, Kenjiro ; Ohashi, Yasuo ; Watanabe, Tsuyoshi. / Control status of atherosclerotic cardiovascular risk factors among Japanese high-risk subjects : Analyses of a Japanese health check database from 2008 to 2011. In: Journal of atherosclerosis and thrombosis. 2016 ; Vol. 23, No. 8. pp. 991-1003.
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abstract = "Aims: Several guidelines propose target levels (TLs) of atherosclerotic risk factors (ARFs) to reduce atherosclerotic cardiovascular diseases; however, few data are available regarding the attainment statuses of TLs in Japan. In this study, utilizing the data obtained from the annual “Specific Health Check and Guidance in Japan” conducted from 2008 to 2011 (approximately 280,000 subjects each year), we determined TL attainments of ARFs in cardiovascular high-risk subjects. Methods: Those who had suffered from cerebrovascular disease (pCVD) or coronary heart disease (pCHD) or were receiving diabetes mellitus treatment (DM) were selected, and the rates of subjects that attained TLs of blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TGs) and glycated hemoglobin (HbA1c) were analyzed. Results: Approximately 70{\%} of pCVD or pCHD and 35{\%} of subjects with DM attained TLs of BP. With regard to HbA1c, >90{\%} of pCVD or pCHD and approximately 50{\%} of subjects with DM attained TLs. With regard to LDL-C, <25{\%} of pCHD females and approximately 35{\%} of pCHD males and 50{\%}-55{\%} of subjects with pCVD or DM attained TLs. The TL-attainment rates of HDL-C and TGs were approximately 90{\%} and 75{\%}, respectively, for the three diseases. Analyses of time course changes in their attainment statuses revealed that the attainment rates of BP and LDL-C significantly improved in all the diseases. Conclusions: TL-attainment rates of BP and LDL-C were not as high as those for HDL-C, TGs, and HbA1c; however, they both showed highly significant improvements during the study period.",
author = "Koji Hasegawa and Kazuhisa Tsukamoto and Motoei Kunimi and Koichi Asahi and Kunitoshi Iseki and Toshiki Moriyama and Kunihiro Yamagata and Kazuhiko Tsuruya and Shouichi Fujimoto and Ichiei Narita and Tsuneo Konta and Masahide Kondo and Kenjiro Kimura and Yasuo Ohashi and Tsuyoshi Watanabe",
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T1 - Control status of atherosclerotic cardiovascular risk factors among Japanese high-risk subjects

T2 - Analyses of a Japanese health check database from 2008 to 2011

AU - Hasegawa, Koji

AU - Tsukamoto, Kazuhisa

AU - Kunimi, Motoei

AU - Asahi, Koichi

AU - Iseki, Kunitoshi

AU - Moriyama, Toshiki

AU - Yamagata, Kunihiro

AU - Tsuruya, Kazuhiko

AU - Fujimoto, Shouichi

AU - Narita, Ichiei

AU - Konta, Tsuneo

AU - Kondo, Masahide

AU - Kimura, Kenjiro

AU - Ohashi, Yasuo

AU - Watanabe, Tsuyoshi

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Aims: Several guidelines propose target levels (TLs) of atherosclerotic risk factors (ARFs) to reduce atherosclerotic cardiovascular diseases; however, few data are available regarding the attainment statuses of TLs in Japan. In this study, utilizing the data obtained from the annual “Specific Health Check and Guidance in Japan” conducted from 2008 to 2011 (approximately 280,000 subjects each year), we determined TL attainments of ARFs in cardiovascular high-risk subjects. Methods: Those who had suffered from cerebrovascular disease (pCVD) or coronary heart disease (pCHD) or were receiving diabetes mellitus treatment (DM) were selected, and the rates of subjects that attained TLs of blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TGs) and glycated hemoglobin (HbA1c) were analyzed. Results: Approximately 70% of pCVD or pCHD and 35% of subjects with DM attained TLs of BP. With regard to HbA1c, >90% of pCVD or pCHD and approximately 50% of subjects with DM attained TLs. With regard to LDL-C, <25% of pCHD females and approximately 35% of pCHD males and 50%-55% of subjects with pCVD or DM attained TLs. The TL-attainment rates of HDL-C and TGs were approximately 90% and 75%, respectively, for the three diseases. Analyses of time course changes in their attainment statuses revealed that the attainment rates of BP and LDL-C significantly improved in all the diseases. Conclusions: TL-attainment rates of BP and LDL-C were not as high as those for HDL-C, TGs, and HbA1c; however, they both showed highly significant improvements during the study period.

AB - Aims: Several guidelines propose target levels (TLs) of atherosclerotic risk factors (ARFs) to reduce atherosclerotic cardiovascular diseases; however, few data are available regarding the attainment statuses of TLs in Japan. In this study, utilizing the data obtained from the annual “Specific Health Check and Guidance in Japan” conducted from 2008 to 2011 (approximately 280,000 subjects each year), we determined TL attainments of ARFs in cardiovascular high-risk subjects. Methods: Those who had suffered from cerebrovascular disease (pCVD) or coronary heart disease (pCHD) or were receiving diabetes mellitus treatment (DM) were selected, and the rates of subjects that attained TLs of blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TGs) and glycated hemoglobin (HbA1c) were analyzed. Results: Approximately 70% of pCVD or pCHD and 35% of subjects with DM attained TLs of BP. With regard to HbA1c, >90% of pCVD or pCHD and approximately 50% of subjects with DM attained TLs. With regard to LDL-C, <25% of pCHD females and approximately 35% of pCHD males and 50%-55% of subjects with pCVD or DM attained TLs. The TL-attainment rates of HDL-C and TGs were approximately 90% and 75%, respectively, for the three diseases. Analyses of time course changes in their attainment statuses revealed that the attainment rates of BP and LDL-C significantly improved in all the diseases. Conclusions: TL-attainment rates of BP and LDL-C were not as high as those for HDL-C, TGs, and HbA1c; however, they both showed highly significant improvements during the study period.

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