TY - JOUR
T1 - Controllable shape selectivity based on highly ordered carbonyl and methyl groups in simple β-structural polypeptide on silica
AU - Shundo, Atsuomi
AU - Mallik, Abul K.
AU - Sakurai, Toshihiko
AU - Takafuji, Makoto
AU - Nagaoka, Shoji
AU - Ihara, Hirotaka
N1 - Funding Information:
This research was supported in part by a Japan Society for the Promotion of Science Fellowship (to A. S.) and Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
PY - 2009/8/21
Y1 - 2009/8/21
N2 - Poly(l-alanine)-grafted porous silica (Sil-Ala22) was prepared by polymerization of N-carboxyanhydride of l-alanine initiated by 3-aminopropylated silica. The retention behaviors of the column packed with Sil-Ala22 were investigated by using alkylbenzenes and polycyclic aromatic hydrocarbons as injection samples in liquid chromatography. The Ala22 phase was in a rigid β-form structure and thus provided specific interaction sites, which were derived from the highly ordered carbonyl and methyl groups. These interaction sites bring unique molecular-shape discriminations: molecular-length and non-planarity selectivity, which are controllable by altering organic solvent used as a part of mobile phase.
AB - Poly(l-alanine)-grafted porous silica (Sil-Ala22) was prepared by polymerization of N-carboxyanhydride of l-alanine initiated by 3-aminopropylated silica. The retention behaviors of the column packed with Sil-Ala22 were investigated by using alkylbenzenes and polycyclic aromatic hydrocarbons as injection samples in liquid chromatography. The Ala22 phase was in a rigid β-form structure and thus provided specific interaction sites, which were derived from the highly ordered carbonyl and methyl groups. These interaction sites bring unique molecular-shape discriminations: molecular-length and non-planarity selectivity, which are controllable by altering organic solvent used as a part of mobile phase.
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U2 - 10.1016/j.chroma.2009.06.075
DO - 10.1016/j.chroma.2009.06.075
M3 - Article
C2 - 19616780
AN - SCOPUS:67651235900
SN - 0021-9673
VL - 1216
SP - 6170
EP - 6176
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - 34
ER -