Controllable shape selectivity based on highly ordered carbonyl and methyl groups in simple β-structural polypeptide on silica

Atsuomi Shundo, Abul K. Mallik, Toshihiko Sakurai, Makoto Takafuji, Shoji Nagaoka, Hirotaka Ihara

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Poly(l-alanine)-grafted porous silica (Sil-Ala 22 ) was prepared by polymerization of N-carboxyanhydride of l-alanine initiated by 3-aminopropylated silica. The retention behaviors of the column packed with Sil-Ala 22 were investigated by using alkylbenzenes and polycyclic aromatic hydrocarbons as injection samples in liquid chromatography. The Ala 22 phase was in a rigid β-form structure and thus provided specific interaction sites, which were derived from the highly ordered carbonyl and methyl groups. These interaction sites bring unique molecular-shape discriminations: molecular-length and non-planarity selectivity, which are controllable by altering organic solvent used as a part of mobile phase.

Original languageEnglish
Pages (from-to)6170-6176
Number of pages7
JournalJournal of Chromatography A
Volume1216
Issue number34
DOIs
Publication statusPublished - Aug 21 2009
Externally publishedYes

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Silicon Dioxide
Alanine
Peptides
Polycyclic Aromatic Hydrocarbons
Liquid chromatography
Liquid Chromatography
Polymerization
Organic solvents
Injections

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Cite this

Controllable shape selectivity based on highly ordered carbonyl and methyl groups in simple β-structural polypeptide on silica. / Shundo, Atsuomi; Mallik, Abul K.; Sakurai, Toshihiko; Takafuji, Makoto; Nagaoka, Shoji; Ihara, Hirotaka.

In: Journal of Chromatography A, Vol. 1216, No. 34, 21.08.2009, p. 6170-6176.

Research output: Contribution to journalArticle

Shundo, Atsuomi ; Mallik, Abul K. ; Sakurai, Toshihiko ; Takafuji, Makoto ; Nagaoka, Shoji ; Ihara, Hirotaka. / Controllable shape selectivity based on highly ordered carbonyl and methyl groups in simple β-structural polypeptide on silica. In: Journal of Chromatography A. 2009 ; Vol. 1216, No. 34. pp. 6170-6176.
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