Controlled organelle transfer between live single cells by using microfluidic device

K. I. Wada, K. Hosokawa, Y. Ito, M. Maeda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We previously reported a novel cell fusion method using microfluidic device, in which paired single-cells were fused through a microslit. This method enabled direct mitochondria transfer to the fusion partner without nuclear mixing [1,2], however, it cannot regulate amount of the mitochondria transferred. We herein report that quantitative control of mitochondria transfer can be performed by using newly developed microfluidic devices. When cell fusion was induced through different length of microtunnels, amount of the mitochondria transferred to the fusion partner decreased according to elongation of the microtunnel length.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages333-334
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Externally publishedYes
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Fingerprint Dive into the research topics of 'Controlled organelle transfer between live single cells by using microfluidic device'. Together they form a unique fingerprint.

Cite this