Controlled stability of the triple-stranded helical structure of a β-1,3-glucan with a chromophoric aromatic moiety at a peripheral position

Masato Ikeda, Shuichi Haraguchi, Munenori Numata, Seiji Shinkai

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We synthesized a semiartificial β-1,3-glucan, curdlan with dialkylaniline groups (CUR-DA), that bears chromophoric aromatic groups at its peripheral positions. Spectroscopic studies as well as microscopic observations indicate that CUR-DA adopts a triple-stranded helical structure in water- or methanol-rich solutions of dimethyl sulfoxide (DMSO). This triple-stranded helical structure exhibits high thermal stability and resistance to base, attributes that are similar to those of the triple-stranded helical structure of native β-1,3-glucans such as schizophyllan. Moreover, we found that the stability of the triple-stranded helical structure can be easily modulated by solvent composition and metal-ion (Zn2+) binding. As β-1,3-ghican polysaccharides are known to serve as "polymeric" hosts, including certain DNA molecules, carbon nanotubes, and conjugated polymers, and complexation occurs only with the single-stranded structure, this information is very useful for the creation of these attractive polymeric composites, the controlled release of DNA, and so on.

Original languageEnglish
Pages (from-to)1290-1298
Number of pages9
JournalChemistry - An Asian Journal
Volume2
Issue number10
DOIs
Publication statusPublished - Oct 16 2007

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Glucans
Sizofiran
Carbon Nanotubes
DNA
Conjugated polymers
Dimethyl Sulfoxide
Complexation
Heat resistance
Polysaccharides
Metal ions
Methanol
Polymers
Thermodynamic stability
Hot Temperature
Metals
Ions
Molecules
Water
Composite materials
Chemical analysis

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Controlled stability of the triple-stranded helical structure of a β-1,3-glucan with a chromophoric aromatic moiety at a peripheral position. / Ikeda, Masato; Haraguchi, Shuichi; Numata, Munenori; Shinkai, Seiji.

In: Chemistry - An Asian Journal, Vol. 2, No. 10, 16.10.2007, p. 1290-1298.

Research output: Contribution to journalArticle

Ikeda, Masato ; Haraguchi, Shuichi ; Numata, Munenori ; Shinkai, Seiji. / Controlled stability of the triple-stranded helical structure of a β-1,3-glucan with a chromophoric aromatic moiety at a peripheral position. In: Chemistry - An Asian Journal. 2007 ; Vol. 2, No. 10. pp. 1290-1298.
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