Controlling stereochemistry in C-C and C-H bond formation with electronically asymmetric organometallics and chiral poisons

J. W. Faller, Maria R. Mazzieri, Jenna Thu Nguyen, Jonathan Parr, Makoto Tokunaga

Research output: Contribution to journalArticlepeer-review

82 Citations (Scopus)

Abstract

Air stable (cyclopentadienyl)Mo(NO)(halide)(η3-allyl) complexes add to aldehydes to yield homoallylic alcohols in high enantioselectivity and diastereoselectivity. A new strategy, chiral poisoning, is applied to asymmetric hydrogenation and the kinetic resolution of allylic alcohols using transition metal catalysts prepared from racemic bis-phosphine ligands.

Original languageEnglish
Pages (from-to)1463-1469
Number of pages7
JournalPure and Applied Chemistry
Volume66
Issue number7
DOIs
Publication statusPublished - Jan 1 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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