Convenient one-pot access to 2: H -3-nitrothiochromenes from 2-bromobenzaldehydes, sodium sulfide and β-nitrostyrenes

Thi Thu Huong Le, Chitose Youhei, Quy Hien Le, Thanh Binh Nguyen, Dinh Hung Mac

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

An efficient synthesis of 2H-3-nitrothiochromenes via a cascade reaction was established. Starting from commercially available o-bromobenzaldehydes and β-nitrostyrenes with sodium sulfide nonahydrate as an inexpensive sulfur source, various substituted thiochromenes were synthesized with high functional group tolerance without any added transition metal catalyst or additive.

Original languageEnglish
Pages (from-to)6355-6358
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume17
Issue number26
DOIs
Publication statusPublished - 2019
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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