Cooperation

Another mechanism of viral evolution

Yuta Shirogane, Shumpei Watanabe, Yusuke Yanagi

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution. This type of cooperation between genomes producing a new phenotype may have implications for various aspects of evolution, including the expansion of viral tropism and host range, the emergence of segmented viral genomes, and the evolution of heteromultimeric molecules. It also lends support to the concept of the quasispecies acting as a unit of selection.

Original languageEnglish
Pages (from-to)320-324
Number of pages5
JournalTrends in Microbiology
Volume21
Issue number7
DOIs
Publication statusPublished - Jul 1 2013

Fingerprint

Viral Tropism
Genome
Measles virus
Viral Genome
Host Specificity
RNA Viruses
Viral RNA
Viral Proteins
DNA-Directed RNA Polymerases
Phenotype
Pressure

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

Cite this

Cooperation : Another mechanism of viral evolution. / Shirogane, Yuta; Watanabe, Shumpei; Yanagi, Yusuke.

In: Trends in Microbiology, Vol. 21, No. 7, 01.07.2013, p. 320-324.

Research output: Contribution to journalReview article

@article{31ed3687c0ed421fb21189f864278a9c,
title = "Cooperation: Another mechanism of viral evolution",
abstract = "RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution. This type of cooperation between genomes producing a new phenotype may have implications for various aspects of evolution, including the expansion of viral tropism and host range, the emergence of segmented viral genomes, and the evolution of heteromultimeric molecules. It also lends support to the concept of the quasispecies acting as a unit of selection.",
author = "Yuta Shirogane and Shumpei Watanabe and Yusuke Yanagi",
year = "2013",
month = "7",
day = "1",
doi = "10.1016/j.tim.2013.05.004",
language = "English",
volume = "21",
pages = "320--324",
journal = "Trends in Microbiology",
issn = "0966-842X",
publisher = "Elsevier Limited",
number = "7",

}

TY - JOUR

T1 - Cooperation

T2 - Another mechanism of viral evolution

AU - Shirogane, Yuta

AU - Watanabe, Shumpei

AU - Yanagi, Yusuke

PY - 2013/7/1

Y1 - 2013/7/1

N2 - RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution. This type of cooperation between genomes producing a new phenotype may have implications for various aspects of evolution, including the expansion of viral tropism and host range, the emergence of segmented viral genomes, and the evolution of heteromultimeric molecules. It also lends support to the concept of the quasispecies acting as a unit of selection.

AB - RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution. This type of cooperation between genomes producing a new phenotype may have implications for various aspects of evolution, including the expansion of viral tropism and host range, the emergence of segmented viral genomes, and the evolution of heteromultimeric molecules. It also lends support to the concept of the quasispecies acting as a unit of selection.

UR - http://www.scopus.com/inward/record.url?scp=84879703691&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879703691&partnerID=8YFLogxK

U2 - 10.1016/j.tim.2013.05.004

DO - 10.1016/j.tim.2013.05.004

M3 - Review article

VL - 21

SP - 320

EP - 324

JO - Trends in Microbiology

JF - Trends in Microbiology

SN - 0966-842X

IS - 7

ER -