Cooperation between giant DNA molecules and actin filaments in a microsphere

Makiko Negishi, Takahiro Sakaue, Kingo Takiguchi, Kenichi Yoshikawa

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We report the appearance of a spatially segregated state in a microsphere as a result of cooperation between actin filaments and giant DNA molecules. When the coexisting actin concentration is high enough, DNA molecules are excluded toward the surface by forming an assembly with actin filaments. With a decrease in the actin concentration, actin filaments tend to dissolve within the sphere whereas DNA molecules remain to be excluded onto the surface. When the actin concentration becomes still lower, DNA molecules dissolve within the sphere by avoiding surface attachment. We interpret these experimental trends by introducing the concept of an "exclusion zone" for actin filaments within a microsphere.

Original languageEnglish
Article number051921
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume81
Issue number5
DOIs
Publication statusPublished - May 24 2010

Fingerprint

Microspheres
Actin
Filament
filaments
deoxyribonucleic acid
Molecules
molecules
exclusion
attachment
assembly
trends
Tend
Decrease

All Science Journal Classification (ASJC) codes

  • Statistical and Nonlinear Physics
  • Statistics and Probability
  • Condensed Matter Physics

Cite this

Cooperation between giant DNA molecules and actin filaments in a microsphere. / Negishi, Makiko; Sakaue, Takahiro; Takiguchi, Kingo; Yoshikawa, Kenichi.

In: Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, Vol. 81, No. 5, 051921, 24.05.2010.

Research output: Contribution to journalArticle

Negishi, Makiko ; Sakaue, Takahiro ; Takiguchi, Kingo ; Yoshikawa, Kenichi. / Cooperation between giant DNA molecules and actin filaments in a microsphere. In: Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 2010 ; Vol. 81, No. 5.
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