The first catalytic enantioselective nucleophilic borylation of a
A series of aldehydes reacted with a diboron reagent in the presence of a copper(I)/DTBM-SEGPHOS complex catalyst using MeOH as a proton source to give the corresponding optically active α-alkoxyorganoboronate esters with excellent enantioselectivities. Furthermore, the products could be readily converted to the corresponding functionalized chiral alcohol derivatives through stereospecific C-C bond forming reactions involving the stereogenic C-B bond.
|Number of pages||5|
|Journal||Journal of the American Chemical Society|
|Publication status||Published - Jan 14 2015|
All Science Journal Classification (ASJC) codes
- Colloid and Surface Chemistry