Correlation between the structure of water in the vicinity of zwitterionic polymers and their bio-compatibility

Susumu Tada; Kohei Takaha; Kyoko Nagaoka; Makoto Gemmei-Ide; Hiromi Kitano; Takayuki Matsunaga; Akira Mochizuki; Masaru Tanaka

Correlation between the structure of water in the vicinity of zwitterionic polymers and their bio-compatibility

Susumu Tada, Kohei Takaha, Kyoko Nagaoka, Makoto Gemmei-Ide, Hiromi Kitano, Takayuki Matsunaga, Akira Mochizuki, Masaru Tanaka

Research output: Contribution to conference › Paper › peer-review

1 Citation (Scopus)

Abstract

The structure of water in the vicinity of zwitterionic polymers including a copolymer composed of anionic and cationic monomer units was analyzed in their aqueous solutions and thin films by using vibrational spectroscopies. In contrast to ordinary polyelectrolytes, zwitterionic polymers had a very small effect on the structure of water, irrespective of its solubility in water. Zwitterionic polymer films showed a good bio- and blood- compatibility with respect to the V79 cell, complement, platelet systems when compared with other polymer films. These results suggest that the structure of water is very important factor to generate bio- and blood- compatibility of polymers.

Original language	English
Pages	4280-4281
Number of pages	2
Publication status	Published - Dec 1 2006
Externally published	Yes
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: Sep 20 2006 → Sep 22 2006

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
Country	Japan
City	Toyama
Period	9/20/06 → 9/22/06

All Science Journal Classification (ASJC) codes

Engineering(all)

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Correlation between the structure of water in the vicinity of zwitterionic polymers and their bio-compatibility. / Tada, Susumu; Takaha, Kohei; Nagaoka, Kyoko; Gemmei-Ide, Makoto; Kitano, Hiromi; Matsunaga, Takayuki; Mochizuki, Akira; Tanaka, Masaru.

2006. 4280-4281 Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Research output: Contribution to conference › Paper › peer-review

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abstract = "The structure of water in the vicinity of zwitterionic polymers including a copolymer composed of anionic and cationic monomer units was analyzed in their aqueous solutions and thin films by using vibrational spectroscopies. In contrast to ordinary polyelectrolytes, zwitterionic polymers had a very small effect on the structure of water, irrespective of its solubility in water. Zwitterionic polymer films showed a good bio- and blood- compatibility with respect to the V79 cell, complement, platelet systems when compared with other polymer films. These results suggest that the structure of water is very important factor to generate bio- and blood- compatibility of polymers.",

author = "Susumu Tada and Kohei Takaha and Kyoko Nagaoka and Makoto Gemmei-Ide and Hiromi Kitano and Takayuki Matsunaga and Akira Mochizuki and Masaru Tanaka",

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T1 - Correlation between the structure of water in the vicinity of zwitterionic polymers and their bio-compatibility

AU - Tada, Susumu

AU - Takaha, Kohei

AU - Nagaoka, Kyoko

AU - Gemmei-Ide, Makoto

AU - Kitano, Hiromi

AU - Matsunaga, Takayuki

AU - Mochizuki, Akira

AU - Tanaka, Masaru

PY - 2006/12/1

Y1 - 2006/12/1

N2 - The structure of water in the vicinity of zwitterionic polymers including a copolymer composed of anionic and cationic monomer units was analyzed in their aqueous solutions and thin films by using vibrational spectroscopies. In contrast to ordinary polyelectrolytes, zwitterionic polymers had a very small effect on the structure of water, irrespective of its solubility in water. Zwitterionic polymer films showed a good bio- and blood- compatibility with respect to the V79 cell, complement, platelet systems when compared with other polymer films. These results suggest that the structure of water is very important factor to generate bio- and blood- compatibility of polymers.

AB - The structure of water in the vicinity of zwitterionic polymers including a copolymer composed of anionic and cationic monomer units was analyzed in their aqueous solutions and thin films by using vibrational spectroscopies. In contrast to ordinary polyelectrolytes, zwitterionic polymers had a very small effect on the structure of water, irrespective of its solubility in water. Zwitterionic polymer films showed a good bio- and blood- compatibility with respect to the V79 cell, complement, platelet systems when compared with other polymer films. These results suggest that the structure of water is very important factor to generate bio- and blood- compatibility of polymers.

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T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

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