Coulometric detection of an analyte in a liquid plug formed in a microflow channel

F. Sassa, H. Laghzali, J. Fukuda, H. Suzuki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Applicability of coulometric detection was tested for the analysis of an analyte in a liquid plug confined in a PDMS microflow channel. A plug prepared in the flow channel was placed on a three-electrode system and hydrogen peroxide was detected. With plugs of a small volume, the depletion of the analyte was rapid, making reproducible amperometric detection difficult particularly when the flow channel was shallow. On the other hand, coulometric detection showed a clear relationship between the generated charge and the concentration. However, when the volume of the plug was large, only a part of the analyte was used for detection, suggesting the possibility to improve the detection sensitivity further. The device was also tested in the detection of L-glutamate.

Original languageEnglish
Title of host publicationTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages955-958
Number of pages4
DOIs
Publication statusPublished - Dec 11 2009
Externally publishedYes
EventTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, United States
Duration: Jun 21 2009Jun 25 2009

Publication series

NameTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Other

OtherTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
CountryUnited States
CityDenver, CO
Period6/21/096/25/09

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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  • Cite this

    Sassa, F., Laghzali, H., Fukuda, J., & Suzuki, H. (2009). Coulometric detection of an analyte in a liquid plug formed in a microflow channel. In TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 955-958). [5285975] (TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems). https://doi.org/10.1109/SENSOR.2009.5285975