Coulometric detection of an analyte in a liquid plug formed in a microflow channel

Fumihiro Sassa, H. Laghzali, J. Fukuda, H. Suzuki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Applicability of coulometric detection was tested for the analysis of an analyte in a liquid plug confined in a PDMS microflow channel. A plug prepared in the flow channel was placed on a three-electrode system and hydrogen peroxide was detected. With plugs of a small volume, the depletion of the analyte was rapid, making reproducible amperometric detection difficult particularly when the flow channel was shallow. On the other hand, coulometric detection showed a clear relationship between the generated charge and the concentration. However, when the volume of the plug was large, only a part of the analyte was used for detection, suggesting the possibility to improve the detection sensitivity further. The device was also tested in the detection of L-glutamate.

Original languageEnglish
Title of host publicationTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages955-958
Number of pages4
DOIs
Publication statusPublished - 2009
Externally publishedYes
EventTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, United States
Duration: Jun 21 2009Jun 25 2009

Other

OtherTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
CountryUnited States
CityDenver, CO
Period6/21/096/25/09

Fingerprint

Channel flow
Liquids
Hydrogen peroxide
Electrodes

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering

Cite this

Sassa, F., Laghzali, H., Fukuda, J., & Suzuki, H. (2009). Coulometric detection of an analyte in a liquid plug formed in a microflow channel. In TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 955-958). [5285975] https://doi.org/10.1109/SENSOR.2009.5285975

Coulometric detection of an analyte in a liquid plug formed in a microflow channel. / Sassa, Fumihiro; Laghzali, H.; Fukuda, J.; Suzuki, H.

TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems. 2009. p. 955-958 5285975.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sassa, F, Laghzali, H, Fukuda, J & Suzuki, H 2009, Coulometric detection of an analyte in a liquid plug formed in a microflow channel. in TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems., 5285975, pp. 955-958, TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems, Denver, CO, United States, 6/21/09. https://doi.org/10.1109/SENSOR.2009.5285975
Sassa F, Laghzali H, Fukuda J, Suzuki H. Coulometric detection of an analyte in a liquid plug formed in a microflow channel. In TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems. 2009. p. 955-958. 5285975 https://doi.org/10.1109/SENSOR.2009.5285975
Sassa, Fumihiro ; Laghzali, H. ; Fukuda, J. ; Suzuki, H. / Coulometric detection of an analyte in a liquid plug formed in a microflow channel. TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems. 2009. pp. 955-958
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