Critical aspects of [NiFe]hydrogenase ligand composition

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    Abstract

    Structural analysis of the resting state of [NiFe]hydrogenase ([NiFe]H 2ase) shows that the active site has a characteristic bis(μ-thiolato)NiFe unit, where the Ni atom and the Fe atom are bridged by an undetermined oxygen-bearing ligand. This ligand probably derives from the aqueous solvent and is therefore most likely to be H2O, OH - or O2-. Here, we compare the reactivities of a NiFe and a NiRu complex when bearing either acetonitrile or aqueous ligands and demonstrate the critical role of an aqueous ligand in hydrogenase and its mimics. We also make observations on the necessity of organometallic metal-carbon bonds to the supporting frameworks.

    Original languageEnglish
    Pages (from-to)4304-4309
    Number of pages6
    JournalDalton Transactions
    Issue number22
    DOIs
    Publication statusPublished - Jun 29 2009

    All Science Journal Classification (ASJC) codes

    • Inorganic Chemistry

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