Abstract
In order to identify the role of heparin in the process of cryogel formation, variously sulfonated cellulose (SC) were prepared and their gel forming abilities were evaluated by the measurement of temperature dependence of turbidity in solution mixed with fibronectin, fibrinogen and SC. We found that the SC which sulfonated 100% of 6 position and 36% of 2 position in glucose residue in cellulose displayed excellent performances to form gel. Gel forming profiles of this SG also just fitted with that of heparin. These results is to be expected that the most important chemical structure of heparin for gel forming is the 2nd position in glucose residue.
| Original language | English |
|---|---|
| Pages (from-to) | 460-464 |
| Number of pages | 5 |
| Journal | Japanese Journal of Artificial Organs |
| Volume | 26 |
| Issue number | 2 |
| Publication status | Published - May 6 1997 |
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All Science Journal Classification (ASJC) codes
- Biophysics
Cite this
Cryogel formation by cellulose sulfate. / Komai, Takashi; Miyamoto, Keiichi; Miyashita, Keiichi; Tokita, Masayuki; Ito, Takaharu; Shimizu, Manabu; Kobayashi, Naoyuki; Shakashita, Eiiji.
In: Japanese Journal of Artificial Organs, Vol. 26, No. 2, 06.05.1997, p. 460-464.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cryogel formation by cellulose sulfate
AU - Komai, Takashi
AU - Miyamoto, Keiichi
AU - Miyashita, Keiichi
AU - Tokita, Masayuki
AU - Ito, Takaharu
AU - Shimizu, Manabu
AU - Kobayashi, Naoyuki
AU - Shakashita, Eiiji
PY - 1997/5/6
Y1 - 1997/5/6
N2 - In order to identify the role of heparin in the process of cryogel formation, variously sulfonated cellulose (SC) were prepared and their gel forming abilities were evaluated by the measurement of temperature dependence of turbidity in solution mixed with fibronectin, fibrinogen and SC. We found that the SC which sulfonated 100% of 6 position and 36% of 2 position in glucose residue in cellulose displayed excellent performances to form gel. Gel forming profiles of this SG also just fitted with that of heparin. These results is to be expected that the most important chemical structure of heparin for gel forming is the 2nd position in glucose residue.
AB - In order to identify the role of heparin in the process of cryogel formation, variously sulfonated cellulose (SC) were prepared and their gel forming abilities were evaluated by the measurement of temperature dependence of turbidity in solution mixed with fibronectin, fibrinogen and SC. We found that the SC which sulfonated 100% of 6 position and 36% of 2 position in glucose residue in cellulose displayed excellent performances to form gel. Gel forming profiles of this SG also just fitted with that of heparin. These results is to be expected that the most important chemical structure of heparin for gel forming is the 2nd position in glucose residue.
UR - http://www.scopus.com/inward/record.url?scp=0031002623&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031002623&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0031002623
VL - 26
SP - 460
EP - 464
JO - Japanese Journal of Artificial Organs
JF - Japanese Journal of Artificial Organs
SN - 0300-0818
IS - 2
ER -