Current source imaging for high spatial resolution magnetocardiography in normal and abnormal rat cardiac muscles

S. Uchida, K. Iramina, K. Goto, S. Ueno

Research output: Contribution to journalConference article

10 Citations (Scopus)

Abstract

The purpose of our study was to identify the current source produced by acute ischemia and infarction. We measured magnetocardiograms (MCG) and electrocardiograms (ECG) of five male rats using a high-resolution dc superconducting quantum interference device gradiometer in a magnetically shielded room after performing coronary artery occlusion. The spatial resolution of the detecting magnetic field of our system is higher than the typical system, thus permitting the measurement of magnetic fields in small animals. Distribution of the magnetic fields B(t) and distribution of |rot B(t)|, which corresponded to the distribution of the current source, were imaged by 12-channel MCGs. As a result, the distribution of current source changes in the affected area of the myocardium during the ST segment, and amplitude of the peak significantly increased after occlusion. Our system can be used to help clarify the mechanism of the ST shift related to severe heart disease.

Original languageEnglish
Pages (from-to)6205-6207
Number of pages3
JournalJournal of Applied Physics
Volume87
Issue number9 III
DOIs
Publication statusPublished - May 1 2000
Externally publishedYes
Event44th Annual Conference on Magnetism and Magnetic Materials - San Jose, CA, United States
Duration: Nov 15 1999Nov 18 1999

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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