Abstract
Surgery, radiation and chemotherapy are three major therapies for cancer. But now, hope is being gathered in immunotherapy as a treatment for fourth. Immunotherapy has been done than before, but they are non-specific immunotherapy. Those that have become hot topics are specific immunotherapies targeting certain molecules or antigens. In this chapter, current status and prospects of immunotherapy for castration-resistant prostate cancer (CRPC) are described. As concrete examples, Sipuleucel-T(Provenge), GVAX, PROSTVAC-VF, Ipilimumab (anti-CTLA-4 mAb), anti-PD-1 mAb and anti-PSMA mAb are cited. As a result, it is not obtained results which therapy also satisfactory at present. Because of its uncertainties we are in the developmental stages of this therapy and improved outcomes might be achievable.
Original language | English |
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Pages (from-to) | 2174-2178 |
Number of pages | 5 |
Journal | Nihon rinsho. Japanese journal of clinical medicine |
Volume | 72 |
Issue number | 12 |
Publication status | Published - Dec 1 2014 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Medicine(all)