Custom-made titanium devices as membranes for bone augmentation in implant treatment: Clinical application and the comparison with conventional titanium mesh

Tomoki Sumida, Naruto Otawa, Yu Kamata, Satoshi Kamakura, Tomiharu Mtsushita, Hisashi Kitagaki, Shigeo Mori, Kiyoyuki Sasaki, Shunsuke Fujibayashi, Mitsuru Takemoto, Atsushi Yamaguchi, Taiji Sohmura, Takashi Nakamura, Yoshihide Mori

Research output: Contribution to journalArticle

26 Citations (Scopus)


Objective Development of new custom-made devices to reconstruct alveolar bone for implantation, and comparison with conventional methods were the goals of this study. Materials and methods Using a computer-aided design technique, three-dimensional images were constructed. From these data, custom-made devices were produced by a selective laser melting method with pure titanium. Clinical trials also have been conducted with 26 participants who needed bone reconstruction before implantation; they were divided into 2 groups with 13 patients each. The first group uses custom-made devices; the other uses commercial titanium meshes that need to bend during operation. Some clinical aspects are evaluated after the trial. Results The custom-made devices can be produced closely by following the data precisely. Devices are fit for bone defect site. Moreover, the operation time of the custom-made group (75.4 ± 11.6 min) was significantly shorter than that of the conventional group (111.9 ± 17.8 min) (p < 0.01). Mucosal rupture occurs, without significant difference (p = 0.27), in a patient in the custom-made without severe infection (7.7%), and 3 in conventional (23.1%), respectively. The retaining screw is significantly fewer in the custom-made group than commercial mesh group (p < 0.01). Conclusion These results indicate that our novel protocol could be simple and safe for providing powerful support for guided bone regeneration.

Original languageEnglish
Pages (from-to)2183-2188
Number of pages6
JournalJournal of Cranio-Maxillofacial Surgery
Issue number10
Publication statusPublished - Dec 1 2015


All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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