Although hemodialysis has permitted long-term survival of patients with renal failure, β2 microglobulin-derived amyloidosis is a serious complication occurring most commonly in long-term hemodialysis patients. Orthopedic manifestations are quite common, but cutaneous and lingual manifestations are relatively uncommon. We report a 56-year-old patient with lichenoid plaque type of skin eruptions and lingual papules caused by β2 microglobulin-derived amyloidosis. Immunohistochemical study showed that amyloid deposits were positive for anti-β2 microglobulin antibody, but negative for anti-advanced glycation end products antibody (anti-CML and CLE antibody). We discuss the histological and the clinical features of skin manifestations of β2 microglobulin-derived amyloidosis.
|Number of pages||3|
|Journal||European Journal of Dermatology|
|Publication status||Published - Jul 2003|
All Science Journal Classification (ASJC) codes