Cutaneous and lingual papules as a sign of β2 microglobulin-derived amyloidosis in a long-term hemodialysis patient

Takeshi Uenotsuchi, Shinichi Imafuku, Masaharu Nagata, Hiromaro Kiryu, Keisuke Morita, Tetsuya Koga, Masutaka Furue

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Although hemodialysis has permitted long-term survival of patients with renal failure, β2 microglobulin-derived amyloidosis is a serious complication occurring most commonly in long-term hemodialysis patients. Orthopedic manifestations are quite common, but cutaneous and lingual manifestations are relatively uncommon. We report a 56-year-old patient with lichenoid plaque type of skin eruptions and lingual papules caused by β2 microglobulin-derived amyloidosis. Immunohistochemical study showed that amyloid deposits were positive for anti-β2 microglobulin antibody, but negative for anti-advanced glycation end products antibody (anti-CML and CLE antibody). We discuss the histological and the clinical features of skin manifestations of β2 microglobulin-derived amyloidosis.

Original languageEnglish
Pages (from-to)393-395
Number of pages3
JournalEuropean Journal of Dermatology
Volume13
Issue number4
Publication statusPublished - Jul 1 2003

Fingerprint

Amyloidosis
Tongue
Renal Dialysis
Skin Manifestations
Skin
Anti-Idiotypic Antibodies
Advanced Glycosylation End Products
Amyloid Plaques
Renal Insufficiency
Orthopedics
Survival
Antibodies

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Cutaneous and lingual papules as a sign of β2 microglobulin-derived amyloidosis in a long-term hemodialysis patient. / Uenotsuchi, Takeshi; Imafuku, Shinichi; Nagata, Masaharu; Kiryu, Hiromaro; Morita, Keisuke; Koga, Tetsuya; Furue, Masutaka.

In: European Journal of Dermatology, Vol. 13, No. 4, 01.07.2003, p. 393-395.

Research output: Contribution to journalArticle

Uenotsuchi, T, Imafuku, S, Nagata, M, Kiryu, H, Morita, K, Koga, T & Furue, M 2003, 'Cutaneous and lingual papules as a sign of β2 microglobulin-derived amyloidosis in a long-term hemodialysis patient', European Journal of Dermatology, vol. 13, no. 4, pp. 393-395.
Uenotsuchi, Takeshi ; Imafuku, Shinichi ; Nagata, Masaharu ; Kiryu, Hiromaro ; Morita, Keisuke ; Koga, Tetsuya ; Furue, Masutaka. / Cutaneous and lingual papules as a sign of β2 microglobulin-derived amyloidosis in a long-term hemodialysis patient. In: European Journal of Dermatology. 2003 ; Vol. 13, No. 4. pp. 393-395.
@article{84b00173644c4f6dbb62bb53b6c6d86b,
title = "Cutaneous and lingual papules as a sign of β2 microglobulin-derived amyloidosis in a long-term hemodialysis patient",
abstract = "Although hemodialysis has permitted long-term survival of patients with renal failure, β2 microglobulin-derived amyloidosis is a serious complication occurring most commonly in long-term hemodialysis patients. Orthopedic manifestations are quite common, but cutaneous and lingual manifestations are relatively uncommon. We report a 56-year-old patient with lichenoid plaque type of skin eruptions and lingual papules caused by β2 microglobulin-derived amyloidosis. Immunohistochemical study showed that amyloid deposits were positive for anti-β2 microglobulin antibody, but negative for anti-advanced glycation end products antibody (anti-CML and CLE antibody). We discuss the histological and the clinical features of skin manifestations of β2 microglobulin-derived amyloidosis.",
author = "Takeshi Uenotsuchi and Shinichi Imafuku and Masaharu Nagata and Hiromaro Kiryu and Keisuke Morita and Tetsuya Koga and Masutaka Furue",
year = "2003",
month = "7",
day = "1",
language = "English",
volume = "13",
pages = "393--395",
journal = "European Journal of Dermatology",
issn = "1167-1122",
publisher = "John Libbey Eurotext",
number = "4",

}

TY - JOUR

T1 - Cutaneous and lingual papules as a sign of β2 microglobulin-derived amyloidosis in a long-term hemodialysis patient

AU - Uenotsuchi, Takeshi

AU - Imafuku, Shinichi

AU - Nagata, Masaharu

AU - Kiryu, Hiromaro

AU - Morita, Keisuke

AU - Koga, Tetsuya

AU - Furue, Masutaka

PY - 2003/7/1

Y1 - 2003/7/1

N2 - Although hemodialysis has permitted long-term survival of patients with renal failure, β2 microglobulin-derived amyloidosis is a serious complication occurring most commonly in long-term hemodialysis patients. Orthopedic manifestations are quite common, but cutaneous and lingual manifestations are relatively uncommon. We report a 56-year-old patient with lichenoid plaque type of skin eruptions and lingual papules caused by β2 microglobulin-derived amyloidosis. Immunohistochemical study showed that amyloid deposits were positive for anti-β2 microglobulin antibody, but negative for anti-advanced glycation end products antibody (anti-CML and CLE antibody). We discuss the histological and the clinical features of skin manifestations of β2 microglobulin-derived amyloidosis.

AB - Although hemodialysis has permitted long-term survival of patients with renal failure, β2 microglobulin-derived amyloidosis is a serious complication occurring most commonly in long-term hemodialysis patients. Orthopedic manifestations are quite common, but cutaneous and lingual manifestations are relatively uncommon. We report a 56-year-old patient with lichenoid plaque type of skin eruptions and lingual papules caused by β2 microglobulin-derived amyloidosis. Immunohistochemical study showed that amyloid deposits were positive for anti-β2 microglobulin antibody, but negative for anti-advanced glycation end products antibody (anti-CML and CLE antibody). We discuss the histological and the clinical features of skin manifestations of β2 microglobulin-derived amyloidosis.

UR - http://www.scopus.com/inward/record.url?scp=0042661111&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042661111&partnerID=8YFLogxK

M3 - Article

C2 - 12948922

AN - SCOPUS:0042661111

VL - 13

SP - 393

EP - 395

JO - European Journal of Dermatology

JF - European Journal of Dermatology

SN - 1167-1122

IS - 4

ER -