Cycloaddition of lithium ynolate to imines: Synthesis of 3,4-disubstituted β-lactams

Mitsuru Shindo, Soichiro Oya, Yusuke Sato, Kozo Shishido

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

Cycloaddition reaction of a lithium ynolate to N-sulfonylimines afforded 3,4-disubstituted β-lactams. The cis-products were synthesized in high diastereoselectivity via quenching of the intermediate, β-lactam enolates, with phenol.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalHeterocycles
Volume49
Issue number1
DOIs
Publication statusPublished - Dec 31 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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