Cyclophosphamide-induced cardiomyopathy in a patient with seminoma and a history of mediastinal irradiation

Kenjirou Kamezaki, Takahiro Fukuda, Shigeyoshi Makino, Mine Harada

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

A 17-year-old man with mediastinal seminoma was treated with chemotherapy and mediastinal irradiation therapy. Then he received high-dose chemotherapy containing cyclophosphamide (CY) followed by autologous peripheral blood stem cell transplantation. He suffered from CY-induced cardiomyopathy beginning six days after the administration of high-dose CY. The predictable factors associated with the onset of CY-induced cardiomyopathy are not precisely known. It is suggested that the history of mediastinal irradiation was responsible for the onset of cardiomyopathy.

Original languageEnglish
Pages (from-to)120-123
Number of pages4
JournalInternal Medicine
Volume44
Issue number2
DOIs
Publication statusPublished - Feb 1 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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