Abstract
γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted on a silicone elastomer by emulsion polymerization in order to improve cytocompatibility. The wettability of the grafted surface was evaluated with a contact angle toward distilled water. By grafting within 30 min at 60°C, the contact angle was reduced from 110° to about 70° while it remained almost constant for longer grafting. A larger number of osteoblastic cells (MC3T3-E1) and fibroblast cells (1929) proliferated on the surface modified with γ-MPS compared with the original silicone surface. After culturing for 7 d, the cells completely covered the grafted surface and even formed a cell layer.
| Original language | English |
|---|---|
| Pages (from-to) | 72-76 |
| Number of pages | 5 |
| Journal | Journal of the Ceramic Society of Japan |
| Volume | 114 |
| Issue number | 1325 |
| DOIs | |
| Publication status | Published - Jan 1 2006 |
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All Science Journal Classification (ASJC) codes
- Ceramics and Composites
- Chemistry(all)
- Condensed Matter Physics
- Materials Chemistry
Cite this
Cytocompatibility of silicone elastomer grafted with γ-Methacryloxypropyltrimethoxysilane. / Shirosaki, Yuki; Tsuru, Kanji; Hayakawa, Satoshi; Osaka, Akiyoshi; Takashima, Seisuke.
In: Journal of the Ceramic Society of Japan, Vol. 114, No. 1325, 01.01.2006, p. 72-76.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cytocompatibility of silicone elastomer grafted with γ-Methacryloxypropyltrimethoxysilane
AU - Shirosaki, Yuki
AU - Tsuru, Kanji
AU - Hayakawa, Satoshi
AU - Osaka, Akiyoshi
AU - Takashima, Seisuke
PY - 2006/1/1
Y1 - 2006/1/1
N2 - γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted on a silicone elastomer by emulsion polymerization in order to improve cytocompatibility. The wettability of the grafted surface was evaluated with a contact angle toward distilled water. By grafting within 30 min at 60°C, the contact angle was reduced from 110° to about 70° while it remained almost constant for longer grafting. A larger number of osteoblastic cells (MC3T3-E1) and fibroblast cells (1929) proliferated on the surface modified with γ-MPS compared with the original silicone surface. After culturing for 7 d, the cells completely covered the grafted surface and even formed a cell layer.
AB - γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted on a silicone elastomer by emulsion polymerization in order to improve cytocompatibility. The wettability of the grafted surface was evaluated with a contact angle toward distilled water. By grafting within 30 min at 60°C, the contact angle was reduced from 110° to about 70° while it remained almost constant for longer grafting. A larger number of osteoblastic cells (MC3T3-E1) and fibroblast cells (1929) proliferated on the surface modified with γ-MPS compared with the original silicone surface. After culturing for 7 d, the cells completely covered the grafted surface and even formed a cell layer.
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UR - http://www.scopus.com/inward/citedby.url?scp=31144471224&partnerID=8YFLogxK
U2 - 10.2109/jcersj.114.72
DO - 10.2109/jcersj.114.72
M3 - Article
AN - SCOPUS:31144471224
VL - 114
SP - 72
EP - 76
JO - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
JF - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
SN - 1882-0743
IS - 1325
ER -