TY - JOUR
T1 - Cytocompatibility of silicone elastomer grafted with γ-Methacryloxypropyltrimethoxysilane
AU - Shirosaki, Yuki
AU - Tsuru, Kanji
AU - Hayakawa, Satoshi
AU - Osaka, Akiyoshi
AU - Takashima, Seisuke
PY - 2006/1/1
Y1 - 2006/1/1
N2 - γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted on a silicone elastomer by emulsion polymerization in order to improve cytocompatibility. The wettability of the grafted surface was evaluated with a contact angle toward distilled water. By grafting within 30 min at 60°C, the contact angle was reduced from 110° to about 70° while it remained almost constant for longer grafting. A larger number of osteoblastic cells (MC3T3-E1) and fibroblast cells (1929) proliferated on the surface modified with γ-MPS compared with the original silicone surface. After culturing for 7 d, the cells completely covered the grafted surface and even formed a cell layer.
AB - γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted on a silicone elastomer by emulsion polymerization in order to improve cytocompatibility. The wettability of the grafted surface was evaluated with a contact angle toward distilled water. By grafting within 30 min at 60°C, the contact angle was reduced from 110° to about 70° while it remained almost constant for longer grafting. A larger number of osteoblastic cells (MC3T3-E1) and fibroblast cells (1929) proliferated on the surface modified with γ-MPS compared with the original silicone surface. After culturing for 7 d, the cells completely covered the grafted surface and even formed a cell layer.
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U2 - 10.2109/jcersj.114.72
DO - 10.2109/jcersj.114.72
M3 - Article
AN - SCOPUS:31144471224
VL - 114
SP - 72
EP - 76
JO - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
JF - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
SN - 1882-0743
IS - 1325
ER -