Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages

Tetsuya Hayashi, Hideki Matsumoto, Makoto Ohnishi, Shin ichi Yokota, Tomoyuki Shinomiya, Makoto Kageyama, Yoshiro Terawaki

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

φCTX is a temperate phage of Pseudomonas aeruginosa harbouring the ctx gene that encodes cytotoxin (CTX). We identified φCTX as an R pyocin-related phage, by serological and molecular analysis, based on the findings that the infectivity of the phage was inhibited with the antisera directed R pyocins and R pyocin-related phages and that the φCTX genome showed DNA homology to the genome of PS17 (a representative of the R pyocin-related phages) as well as to the pyocin R2 genes. Another new CTX-converting, R pyocin-related phage named PS21 was isolated from a CTX-producing strain of P. aeruginosa, suggesting the distribution of the ctx gene by certain members of R pyocin-related phage family.

Original languageEnglish
Pages (from-to)239-244
Number of pages6
JournalFEMS microbiology letters
Volume122
Issue number3
Publication statusPublished - Oct 1 1994

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Pyocins
Cytotoxins
Bacteriophages
Pseudomonas aeruginosa
Genome
Genes
Immune Sera

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology
  • Genetics

Cite this

Hayashi, T., Matsumoto, H., Ohnishi, M., Yokota, S. I., Shinomiya, T., Kageyama, M., & Terawaki, Y. (1994). Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages. FEMS microbiology letters, 122(3), 239-244.

Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages. / Hayashi, Tetsuya; Matsumoto, Hideki; Ohnishi, Makoto; Yokota, Shin ichi; Shinomiya, Tomoyuki; Kageyama, Makoto; Terawaki, Yoshiro.

In: FEMS microbiology letters, Vol. 122, No. 3, 01.10.1994, p. 239-244.

Research output: Contribution to journalArticle

Hayashi, T, Matsumoto, H, Ohnishi, M, Yokota, SI, Shinomiya, T, Kageyama, M & Terawaki, Y 1994, 'Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages', FEMS microbiology letters, vol. 122, no. 3, pp. 239-244.
Hayashi T, Matsumoto H, Ohnishi M, Yokota SI, Shinomiya T, Kageyama M et al. Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages. FEMS microbiology letters. 1994 Oct 1;122(3):239-244.
Hayashi, Tetsuya ; Matsumoto, Hideki ; Ohnishi, Makoto ; Yokota, Shin ichi ; Shinomiya, Tomoyuki ; Kageyama, Makoto ; Terawaki, Yoshiro. / Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages. In: FEMS microbiology letters. 1994 ; Vol. 122, No. 3. pp. 239-244.
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