Death due to recurrence following curative resection of early gastric cancer depends on age of the patient

S. Moriguchi, T. Odaka, Y. Hayashi, Y. Nose, Y. Maehara, D. Korenaga, K. Sugimachi

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Abstract

This study was done to define the relationship between age at the time of surgery and the prognosis after curative resection for patients with an early gastric cancer. Three hundred and eighty-two patients were identified and 25 patients died of tumour recurrence. Overall, the cumulative survival rate was 94.9% at 5 years and 92.4% at 10 years. Patients with a recurrence of the gastric cancer tended to be older, were more likely to have large differentiated type of tumour and lymph node metastases were often present. Stratified into age-classified groups, the survival rate decreased with increase of age (for patients under age 34 years, 35 to 44, 45 to 54, 55 to 64, 65 to 74, over age 75 years, the 5-year survival rates were 100.0, 97.7, 97.6, 94.2, 94.1 and 84.4 (%)). Of the 25 patients with a tumour recurrence and who died, the survival time of 18 patients over age 55 years was significantly shorter than that of seven patients under age 54 years (median, 1.7 vs 5.6 years, P <0.05). The multivariate analysis showed that, over and above the differentiated type of tumour (P<0.01) and the presence of lymph node metastases (P<0.01), age was one of the prognostic factors (P < 0.05). We conclude that age at the time of primary surgery is a significant factor in patients with an early gastric cancer.

Original languageEnglish
Pages (from-to)555-558
Number of pages4
JournalBritish journal of cancer
Volume64
Issue number3
DOIs
Publication statusPublished - Sep 1991

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Stomach Neoplasms
Recurrence
Survival Rate
Neoplasms
Lymph Nodes
Neoplasm Metastasis
Multivariate Analysis
Age Groups
Survival

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Moriguchi, S., Odaka, T., Hayashi, Y., Nose, Y., Maehara, Y., Korenaga, D., & Sugimachi, K. (1991). Death due to recurrence following curative resection of early gastric cancer depends on age of the patient. British journal of cancer, 64(3), 555-558. https://doi.org/10.1038/bjc.1991.349

Death due to recurrence following curative resection of early gastric cancer depends on age of the patient. / Moriguchi, S.; Odaka, T.; Hayashi, Y.; Nose, Y.; Maehara, Y.; Korenaga, D.; Sugimachi, K.

In: British journal of cancer, Vol. 64, No. 3, 09.1991, p. 555-558.

Research output: Contribution to journalArticle

Moriguchi, S, Odaka, T, Hayashi, Y, Nose, Y, Maehara, Y, Korenaga, D & Sugimachi, K 1991, 'Death due to recurrence following curative resection of early gastric cancer depends on age of the patient', British journal of cancer, vol. 64, no. 3, pp. 555-558. https://doi.org/10.1038/bjc.1991.349
Moriguchi, S. ; Odaka, T. ; Hayashi, Y. ; Nose, Y. ; Maehara, Y. ; Korenaga, D. ; Sugimachi, K. / Death due to recurrence following curative resection of early gastric cancer depends on age of the patient. In: British journal of cancer. 1991 ; Vol. 64, No. 3. pp. 555-558.
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