Decellularized tissue engineering

Nana Shirakigawa, Hiroyuki Ijima

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Tissue Engineering consists of cells, a scaffold and cytokines. Decellularization represents the removal of cells from tissues or organs. Recently, decellularized tissue has been investigated as a scaffold for tissue engineering, termed decellularized tissue engineering. Importantly, the decellularized organ retains its original structure, which is then used as a template for organ construction. The decellularized organ also retains the tissue-specific extracellular matrix. Therefore, decellularized tissue can be used as a matrix to provide a suitable microenvironment for inoculated cells. Based on these concepts, the reconstruction of tissues/organs with decellularized tissue/organ has been attempted using decellularized tissue engineering. In this chapter, we introduce the typical methods used, history and attainment level for the reconstruction of specific tissues/organs. First, the different decellularized techniques and characteristics are introduced. Then, the commonly used analysis methods and cautionary points during decellularization and reconstruction with decellularized tissues/organs are explained. Next, the specific methods and characteristics of decellularized tissue engineering for specific tissues/organs are introduced. In these sections, the current conditions, problems and future work are explained. Finally, we conclude with a summary of this chapter.

Original languageEnglish
Title of host publicationAdvanced Structured Materials
PublisherSpringer Verlag
Pages185-226
Number of pages42
DOIs
Publication statusPublished - Jan 1 2017

Publication series

NameAdvanced Structured Materials
Volume66
ISSN (Print)1869-8433
ISSN (Electronic)1869-8441

Fingerprint

Tissue engineering
Tissue
Scaffolds (biology)
Cytokines

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Cite this

Shirakigawa, N., & Ijima, H. (2017). Decellularized tissue engineering. In Advanced Structured Materials (pp. 185-226). (Advanced Structured Materials; Vol. 66). Springer Verlag. https://doi.org/10.1007/978-981-10-3328-5_5

Decellularized tissue engineering. / Shirakigawa, Nana; Ijima, Hiroyuki.

Advanced Structured Materials. Springer Verlag, 2017. p. 185-226 (Advanced Structured Materials; Vol. 66).

Research output: Chapter in Book/Report/Conference proceedingChapter

Shirakigawa, N & Ijima, H 2017, Decellularized tissue engineering. in Advanced Structured Materials. Advanced Structured Materials, vol. 66, Springer Verlag, pp. 185-226. https://doi.org/10.1007/978-981-10-3328-5_5
Shirakigawa N, Ijima H. Decellularized tissue engineering. In Advanced Structured Materials. Springer Verlag. 2017. p. 185-226. (Advanced Structured Materials). https://doi.org/10.1007/978-981-10-3328-5_5
Shirakigawa, Nana ; Ijima, Hiroyuki. / Decellularized tissue engineering. Advanced Structured Materials. Springer Verlag, 2017. pp. 185-226 (Advanced Structured Materials).
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