TY - GEN
T1 - Degas-driven microfluidic deterministic lateral displacement
AU - Tottori, Naotomo
AU - Nisisako, Takasi
PY - 2018/1/1
Y1 - 2018/1/1
N2 - We report degas-driven deterministic lateral displacement (DLD) for size-based particles enrichment and separation by using polydimethylsiloxane (PDMS) gas solubility. Unlike conventional DLDs which normally require external pumping equipment, we have employed degas-driven flow of a PDMS device to infuse a sample solution into a DLD array. We have demonstrated DLD-based enrichment and separation of differently sized microbeads. Furthermore, separation of white blood cells (WBCs) and red blood cells (RBCs) in whole blood was also demonstrated.
AB - We report degas-driven deterministic lateral displacement (DLD) for size-based particles enrichment and separation by using polydimethylsiloxane (PDMS) gas solubility. Unlike conventional DLDs which normally require external pumping equipment, we have employed degas-driven flow of a PDMS device to infuse a sample solution into a DLD array. We have demonstrated DLD-based enrichment and separation of differently sized microbeads. Furthermore, separation of white blood cells (WBCs) and red blood cells (RBCs) in whole blood was also demonstrated.
UR - http://www.scopus.com/inward/record.url?scp=85079799388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079799388&partnerID=8YFLogxK
M3 - Conference contribution
T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
SP - 2047
EP - 2048
BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PB - Chemical and Biological Microsystems Society
T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Y2 - 11 November 2018 through 15 November 2018
ER -