Deletion in the 190 kDa antigen gene repeat region of Rickettsia rickettsii

Mitsuru Matsumoto, Yoshiki Tange, Takanori Okada, Yasuhiro Inoue, Takahiko Horiuchi, Yuzuru Kobayashi, Shigeru Fujita

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Abstract

The 190 kDa outer membrane protein of Rickettsia rickettsii is a major immunodominant protective antigen which contains 13 tandem nearly identical repeating sequences. We have identified a deletion in the 190 kDa antigen gene of R. rickettsii strain Smith maintained in the laboratory. The deletion occurred within the repeat region of this gene and the mutated repeat region corresponded to one repeating unit in size.

Original languageEnglish
Pages (from-to)57-62
Number of pages6
JournalMicrobial Pathogenesis
Volume20
Issue number1
DOIs
Publication statusPublished - Jan 1 1996
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Microbiology
  • Infectious Diseases

Cite this

Matsumoto, M., Tange, Y., Okada, T., Inoue, Y., Horiuchi, T., Kobayashi, Y., & Fujita, S. (1996). Deletion in the 190 kDa antigen gene repeat region of Rickettsia rickettsii. Microbial Pathogenesis, 20(1), 57-62. https://doi.org/10.1006/mpat.1996.0005