Delphinidin prevents disuse muscle atrophy and reduces stress-related gene expression

Motoki Murata, Reia Kosaka, Kana Kurihara, Shuya Yamashita, Hirofumi Tachibana

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Delphinidin is a member of the anthocyanidin class of plant pigments. We examined the effects of delphinidin on muscle atrophy. Oral administration of delphinidin suppressed the muscle weight loss induced by mechanical unloading. Microarray analysis showed that delphinidin suppresses the upregulation of oxidative stress-related gene expression, including the expression of Cbl-b. Thus, delphinidin may prevent unloading-mediated muscle atrophy.

Original languageEnglish
Pages (from-to)1636-1640
Number of pages5
JournalBioscience, Biotechnology and Biochemistry
Volume80
Issue number8
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

delphinidin
Atrophic Muscular Disorders
Muscular Atrophy
Gene expression
Muscle
Gene Expression
Unloading
Oxidative stress
Anthocyanins
Microarray Analysis
Microarrays
Pigments
Oral Administration
Weight Loss
Oxidative Stress
Up-Regulation
Muscles

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biotechnology
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Delphinidin prevents disuse muscle atrophy and reduces stress-related gene expression. / Murata, Motoki; Kosaka, Reia; Kurihara, Kana; Yamashita, Shuya; Tachibana, Hirofumi.

In: Bioscience, Biotechnology and Biochemistry, Vol. 80, No. 8, 01.01.2016, p. 1636-1640.

Research output: Contribution to journalArticle

Murata, Motoki ; Kosaka, Reia ; Kurihara, Kana ; Yamashita, Shuya ; Tachibana, Hirofumi. / Delphinidin prevents disuse muscle atrophy and reduces stress-related gene expression. In: Bioscience, Biotechnology and Biochemistry. 2016 ; Vol. 80, No. 8. pp. 1636-1640.
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