Demonstration of reversed flow in segmental branches of the portal vein with hand-held color Doppler ultrasonography after hematopoietic stem cell transplantation

M. Hashiguchi, T. Okamura, K. Yoshimoto, N. Ono, R. Imamura, K. Yakushiji, H. Ogata, R. Seki, K. Otsubo, E. Oku, M. Kuroiwa, M. Higuchi, Koji Kato, S. Taniguchi, H. Gondo, T. Shibuya, K. Nagafuji, M. Harada, M. Sata

Research output: Contribution to journalArticle

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Abstract

Hepatic veno-occlusive disease (VOD) is a severe complication of hematopoietic stem cell transplantation (SCT). When monitored with hand-held color Doppler ultrasonography during day -7 to +35 around SCT, reversed blood flow in the segmental branches of the portal vein was detected in nine of 56 patients who had undergone SCT. Three of nine patients had clinical evidence of VOD, but six patients did not fulfill the criteria for diagnosis of VOD initially. Two patients progressed to clinical VOD at a later date and the reversed portal flow disappeared with or without treatment for VOD in the other four patients. Monitoring for reversed portal flow with color Doppler ultrasonography may be a useful tool for the early diagnosis of VOD, and may improve prognosis by allowing early initiation of treatment.

Original languageEnglish
Pages (from-to)1071-1075
Number of pages5
JournalBone Marrow Transplantation
Volume36
Issue number12
DOIs
Publication statusPublished - Dec 1 2005

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Doppler Color Ultrasonography
Hematopoietic Stem Cell Transplantation
Portal Vein
Hand
Stem Cell Transplantation
Hepatic Veno-Occlusive Disease
Early Diagnosis
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hematology
  • Transplantation

Cite this

Demonstration of reversed flow in segmental branches of the portal vein with hand-held color Doppler ultrasonography after hematopoietic stem cell transplantation. / Hashiguchi, M.; Okamura, T.; Yoshimoto, K.; Ono, N.; Imamura, R.; Yakushiji, K.; Ogata, H.; Seki, R.; Otsubo, K.; Oku, E.; Kuroiwa, M.; Higuchi, M.; Kato, Koji; Taniguchi, S.; Gondo, H.; Shibuya, T.; Nagafuji, K.; Harada, M.; Sata, M.

In: Bone Marrow Transplantation, Vol. 36, No. 12, 01.12.2005, p. 1071-1075.

Research output: Contribution to journalArticle

Hashiguchi, M, Okamura, T, Yoshimoto, K, Ono, N, Imamura, R, Yakushiji, K, Ogata, H, Seki, R, Otsubo, K, Oku, E, Kuroiwa, M, Higuchi, M, Kato, K, Taniguchi, S, Gondo, H, Shibuya, T, Nagafuji, K, Harada, M & Sata, M 2005, 'Demonstration of reversed flow in segmental branches of the portal vein with hand-held color Doppler ultrasonography after hematopoietic stem cell transplantation', Bone Marrow Transplantation, vol. 36, no. 12, pp. 1071-1075. https://doi.org/10.1038/sj.bmt.1705170
Hashiguchi, M. ; Okamura, T. ; Yoshimoto, K. ; Ono, N. ; Imamura, R. ; Yakushiji, K. ; Ogata, H. ; Seki, R. ; Otsubo, K. ; Oku, E. ; Kuroiwa, M. ; Higuchi, M. ; Kato, Koji ; Taniguchi, S. ; Gondo, H. ; Shibuya, T. ; Nagafuji, K. ; Harada, M. ; Sata, M. / Demonstration of reversed flow in segmental branches of the portal vein with hand-held color Doppler ultrasonography after hematopoietic stem cell transplantation. In: Bone Marrow Transplantation. 2005 ; Vol. 36, No. 12. pp. 1071-1075.
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