Description of a 23.9-kilobase chromosomal deletion containing a region encoding fsr genes which mainly determines the gelatinase-negative phenotype of clinical isolates of enterococcus faecalis in urine

Jiro Nakayama, Reiko Kariyama, Hiromi Kumon

Research output: Contribution to journalArticle

85 Citations (Scopus)

Abstract

Expression of virulence-related extracellular proteases, gelatinase, and serine protease of Enterococcus faecalis is regulated by a quorum-sensing system encoded by the fsr gene cluster. In this study, a 23.9-kb chromosomal deletion containing the fsr gene cluster region was found to be present in the majority (79%) of gelatinase-negative clinical isolates of E. faecalis from urine.

Original languageEnglish
Pages (from-to)3152-3155
Number of pages4
JournalApplied and environmental microbiology
Volume68
Issue number6
DOIs
Publication statusPublished - Jun 18 2002

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Gelatinases
Enterococcus faecalis
Multigene Family
multigene family
urine
phenotype
Urine
Phenotype
Quorum Sensing
quorum sensing
gene
Serine Proteases
serine proteinases
virulence
Genes
Virulence
Peptide Hydrolases
proteinases
genes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

Cite this

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