Design of a multinuclear Zn(ii) complex as a new molecular probe for fluorescence imaging of His-tag fused proteins

Sho Hei Fujishima, Hiroshi Nonaka, Sho Hei Uchinomiya, Yoshiyuki Alex Kawase, Akio Ojida, Itaru Hamachi

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

A Zn(ii) complex (Zn(ii)-Ida) was designed as the new fluorescent probe for His-tag fused proteins. Thanks to the tight binding ability to histidine-rich sequences and bright fluorescence property of the Cy5-appended Zn(ii)-Ida probes, selective and clear fluorescent imaging of the His-tag fused G-protein coupled receptors on live cell surfaces was carried out.

Original languageEnglish
Pages (from-to)594-596
Number of pages3
JournalChemical Communications
Volume48
Issue number4
DOIs
Publication statusPublished - Dec 14 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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