In order to isolate the auxin receptor, we have successfully synthesized two analogues of benzoxazolinones with a trifluoromethyldiazirine group as a photoaffinity probe. These compounds inhibited the auxin-induced growth of etiolated Avena coleoptile segments. Photolyses of these compounds in methanol gave intermolecular O-H insertion products in moderate yields, respectively.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry