Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells

Jeong Hun Kang; Daisuke Asai; Jong Hwan Kim; Takeshi Mori; Riki Toita; Tetsuro Tomiyama; Yoji Asami; Jun Oishi; Yuko T. Sato; Takuro Niidome; Byungdug Jun; Hideki Nakashima; Yoshiki Katayama

doi:10.1021/ja805364s

Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells

Jeong Hun Kang, Daisuke Asai, Jong Hwan Kim, Takeshi Mori, Riki Toita, Tetsuro Tomiyama, Yoji Asami, Jun Oishi, Yuko T. Sato, Takuro Niidome, Byungdug Jun, Hideki Nakashima, Yoshiki Katayama

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

We succeeded in cancer cell specific gene expression by using a polyplex responsive to protein kinase Cα, which is activated in various types of cancer cells.

Original language	English
Pages (from-to)	14906-14907
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	130
Issue number	45
DOIs	https://doi.org/10.1021/ja805364s
Publication status	Published - Nov 12 2008

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ja805364s

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Kang, J. H., Asai, D., Kim, J. H., Mori, T., Toita, R., Tomiyama, T., Asami, Y., Oishi, J., Sato, Y. T., Niidome, T., Jun, B., Nakashima, H., & Katayama, Y. (2008). Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells. Journal of the American Chemical Society, 130(45), 14906-14907. https://doi.org/10.1021/ja805364s

Kang, JH, Asai, D, Kim, JH, Mori, T, Toita, R, Tomiyama, T, Asami, Y, Oishi, J, Sato, YT, Niidome, T, Jun, B, Nakashima, H & Katayama, Y 2008, 'Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells', Journal of the American Chemical Society, vol. 130, no. 45, pp. 14906-14907. https://doi.org/10.1021/ja805364s

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author = "Kang, {Jeong Hun} and Daisuke Asai and Kim, {Jong Hwan} and Takeshi Mori and Riki Toita and Tetsuro Tomiyama and Yoji Asami and Jun Oishi and Sato, {Yuko T.} and Takuro Niidome and Byungdug Jun and Hideki Nakashima and Yoshiki Katayama",

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AU - Mori, Takeshi

AU - Toita, Riki

AU - Tomiyama, Tetsuro

AU - Asami, Yoji

AU - Oishi, Jun

AU - Sato, Yuko T.

AU - Niidome, Takuro

AU - Jun, Byungdug

AU - Nakashima, Hideki

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Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells

Abstract

All Science Journal Classification (ASJC) codes

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