Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells

Jeong Hun Kang, Daisuke Asai, Jong Hwan Kim, Takeshi Mori, Riki Toita, Tetsuro Tomiyama, Yoji Asami, Jun Oishi, Yuko T. Sato, Takuro Niidome, Byungdug Jun, Hideki Nakashima, Yoshiki Katayama

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

We succeeded in cancer cell specific gene expression by using a polyplex responsive to protein kinase Cα, which is activated in various types of cancer cells.

Original languageEnglish
Pages (from-to)14906-14907
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number45
DOIs
Publication statusPublished - Nov 12 2008

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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