Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials

Suguru Beppu, Takumi Makimura, Takeshi Mori, Keiji Minagawa, Masami Tanaka

Research output: Contribution to conferencePaper

Abstract

We synthesized three kinds of α,α-disubstituted vinyl polymers having ester or amide groups (polymer 1, 2, 3), and studied the thermosensitive properties of their aqueous solutions. All of the polymers show phase transition, and 2 and 3 show an unusual thermal hysteresis. It is probably caused by strong hydrogen bonding among the amide groups of polymers. Addition of inorganic salts and urea does not affect this hysteresis. Adhesion of cells to the phase-separated polymer films was investigated.

Original languageEnglish
Pages5264-5265
Number of pages2
Publication statusPublished - Dec 1 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period9/20/069/22/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Beppu, S., Makimura, T., Mori, T., Minagawa, K., & Tanaka, M. (2006). Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials. 5264-5265. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.